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The hERG Cardiac Potassium Channel: Structure, Function and Long QT Syndrome, Novartis Foundation Symposium

The hERG Cardiac Potassium Channel: Structure, Function and Long QT Syndrome, Novartis Foundation Symposium

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Published by Wiley
This book draws together contributions from basic, pharmaceutical and clinical sciences aimed at a better understanding of the structure and function of hERG and the molecular basis for compound binding. 

It features regulatory authority perspectives on preferred preclinical test systems and includes topics on hERG channel gating, regulation of functional expression, pharmacological properties of hERG/IKr channels, drug-induced long QT syndrome and preclinical evaluation and regulatory recommendations for assessing QT prolongation risks. 

Better understanding of the role of the hERG channel in drug-induced cardiac arrhythmias should ultimately lead to the development of important, new and safer medicines.

This book draws together contributions from basic, pharmaceutical and clinical sciences aimed at a better understanding of the structure and function of hERG and the molecular basis for compound binding. 

It features regulatory authority perspectives on preferred preclinical test systems and includes topics on hERG channel gating, regulation of functional expression, pharmacological properties of hERG/IKr channels, drug-induced long QT syndrome and preclinical evaluation and regulatory recommendations for assessing QT prolongation risks. 

Better understanding of the role of the hERG channel in drug-induced cardiac arrhythmias should ultimately lead to the development of important, new and safer medicines.

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Publish date: Jun 14, 2005
Added to Scribd: Jun 02, 2013
Copyright:Traditional Copyright: All rights reservedISBN:9780470021415
List Price: $212.00 Buy Now

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03/02/2015

309

9780470021415

$212.00

USD

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