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RAPID PACKING
Celox RAPID 5Z-Fold packs faster than other 12competitive gauzes. RAPID has demonstrated faster packing in both In Vitro and Field Testing. On average, the time taken with Celox RAPID was half of the time with either of the other two products1 (Combat Gauze and ChitoGauze)

RAPID COMPRESSION
Celox RAPID speeds up compression time. This is demonstrable based on in vivo results that are similar or better after one minute than results after three minutes compression for ChitoGauze or Quikclot Combat Gauze in previous studies. Based on independent study, Celox Rapid can eliminate the compression step entirely after packing.2

REDUCED BLOOD LOSS

Celox RAPID demonstrated decreased secondary blood loss in comparison to Combat Gauze.4

STABILITY IN EVACUATION
Celox RAPID maintains its volume and adhesion to wet tissue during use, helping it to stay in place during patient transport and maintain hemostasis during transit. In comparative testing against Chitogauze and Combat Gauze, Celox RAPID demonstrated significantly stronger adhesion after treatment at time intervals of one minute, three minutes and twenty minutes. Because Celox RAPID sticks to wet tissue, its use results in performance benefits including hemostasis speed, reduced blood loss and safer transit of severely wounded patients.3

Chito-R
The positively charged activated chitosan in Chito-R rapidly absorbs blood. This process creates a robust gel plug over the bleeding source independent of the bodys intrinsic clotting cascade. The activated chitosan in Chito-R is a compound of glucosamine and N-acetyl glucosamine, naturally occurring basic sugars. Celox RAPID with Chito-R, addressing the significant capability gap of the current standard of treatment for hemorrhage control. Celox RAPID can eliminate the compression step entirely after packing.
(1) (2) (3) (4) Reduced Application Time with a Rapid Packing Gauze Hemostat Andrew Hoggarth, Craig Hardy, Guy Eason, Chris Marsden (Medtrade Products Ltd, Crewe, UK) Testing a new gauze hemostat with reduced treatment time Hoggarth A1, Hardy C1, Millner R2, Lyon A1 (1: Medtrade Products Ltd, UK, 2: Blackpool Victoria Hospital, UK ) Mechanism of action of rapid-action gauze hemostat Authors: Andrew Hoggarth, Craig Hardy, Guy Eason, Andrew Lyon, Chris Marsden (Medtrade Products Ltd, Crewe, UK) Chitosan based advanced hemostatic dressing is associated with decreased blood loss in a swine uncontrolled hemorrhage model. Presented at the Region X Committee on Trauma annual meeting, Olympia, Wash., Dec, 2011.

MAKE EVERY SECOND COUNT.

IN VITRO TIME TO PACK A WOUND IN SECONDS...

YOU DONT ALWAYS HAVE THREE MINUTES BECAUSE YOU DONT KNOW WHATS COMING NEXT.
TACTICAL APPLICATION
As the occurrences of violent and brutal acts escalates, so too have the demands to provide care under increasingly chaotic and life threatening conditions. Celox RAPID

IMMEDIATE HEMOSTASIS

defines Tactical Hemostasis and bridges the significant capability gap between emerging tactics and the current standard of treatment for hemorrhage control.

MEDICAL FORCE MULTIPLIER

The medical and downstream tactical implications of

POSTTREATMENT BLOOD LOSS (ml)

active shooter, officer down or mass-casualty situations demand high-speed, easy-to-use Tactical Hemostatic products. With Rapid Packing and Minimal Compression, Celox RAPID can reduce hemostasis to a minute or less expanding

SUCCESSFUL TRANSPORT WITHOUT RE-BLEED

the first responders capabilities to care for other wounds or casualties. A 5 Celox RAPID packs faster, requires minimal post-application compression, reduces blood loss, and provides greater stability in evacuation compared to competitive products. Independent in vivo testing showed 100 % success in achieving hemostasis and reduced blood loss compared to other treatments*. Celox RAPID has also been tested in a model of casualty evacuation, achieving 100% successful transport without re-bleeding*.

WET STICK AFTER 1 MINUTE

ACTUAL FIELD TESTING IN SECONDS...

* RAPID Gauze could be rapidly applied on the wound on average within half the time of the predicate devices. Has been proven in controlled trials to stop major arterial bleeding by coagulating the blood within 1 minute, CTOMS.CA reducing blood loss.

THE 3-MINUTE GAUZES...

ARE YOU CARRYING THE BEST?
Celox Gauze had the highest observed survival rate with 90% of the animals surviving, while Combat Gauze had a 60% survival rate.

Celox Gauze, designed and intended for the control of severe bleeding, offers numerous Clinical, Tactical, and Economical advantages over other 3-Minute hemostatic dressings such as Combat Gauze, Combat Gauze XL, and ChitoGauze.

CLINICAL
When placed directly into a bleeding wound and subjected to pressure Celox Gauze absorbs blood and forms a muco-adhesive gel that seals the wound to stop the flow of blood. In a recent Navy Study1, Celox Gauze clearly and consistently outperformed competitors in several areas relevant to a Combat or Tactical Medic. They include: Immediate Hemostasis (defined as a 3 minute compression period), Post-Application Blood Loss, and most notably, Survival. These features present initial and downstream benefits for both the casualty and the medic making Celox Gauze the preferred choice of the 3-Minute Gauzes.

TACTICAL
YOU DONT ALWAYS GET TO CHOOSE YOUR PHASE OF CARE. 3 Minutes of direct pressure begins after dressing application ends. Packs faster can be the difference between your safety and tactical medical superiority for your casualty. Celox 5 Gauze is nearly 60% shorter in length compared to competitive products while filling the same size wound. The shorter gauze allows significantly faster wound packing. Celox 5 Z-Fold Gauze is intuitive, easy to handle, and reduces application time during all phases of care.

ECONOMICAL
Celox Gauze does not double in price for double the volume. For massive traumatic wound packing, Celox Gauze 10 Z-Fold can provide the clinically desired additional volume WITHOUT the double Extra Large product price***. A unit of Celox 10 Gauze is capable of packing more than twice the wound volume of some of its competitors.
(1) Rall JM et al. Comparison of Novel Hemostatic gauzes to Quikclot Combat Gauze in a standardized swine model of uncontrollable hemorrhage.

ONR 2012(1) Standard Swine Model of Uncontrolled Hemorrhage

CELOX GAUZE IS A HIGH PERFORMANCE HEMOSTATIC GAUZE THAT OFFERS CLINICAL, TACTICAL, AND ECONOMICAL ADVANTAGES OVER COMPETITIVE 3-MINUTE GAUZES.
CELOX UTILIZES CHITOSAN, A COMPOUND OF GLUCOSAMINE, A SUGAR THAT IS NORMALLY FOUND IN THE BODY.

Celox-A
THE FIRST HIGH-SPEED HEMOSTATIC DELIVERY SYSTEM FOR GUNSHOT, BLAST, OR STAB WOUNDS.
ACCELERATED
Delivers 6g directly Promotes Rapid Coagulation Works in hypothermic conditions Clots heparnized blood

The applicator was designed to give the caregiver a simple and effective tool to apply Celox to the source of severely bleeding wounds. The Celox-A Applicator has been integrated into thousands of IFAKs to create a comprehensive bleeder kit for shrapnel, IED, gunshot, and knife wounds. When placed directly into a bleeding wound and subjected to pressure CELOX absorbs blood and forms an adhesive gel that seals the wound to stop the flow of blood. Celox has repeatedly and reliably demonstrated the ability to stop arterial bleeding in independent US Navy severe bleeding tests1. In a published 2011 comparison2, Celox-A outperformed Combat Gauze in a lethal penetrating trauma model in both Initial Hemostasis and Survival.
(1) Kozen B et al. An alternative hemostatic dressing: comparison of CELOX, Hemcon and Quikclot. J Acad Emerg Med 2008: 15; 74-81. January 2008, Vol 15 No 1. (2) Littlejohn LF et al. Acad Emerg Med 2011: 18; 340-350.

Celox-GRANULES
WHEN MIXED WITH BLOOD, CELOX FORMS A ROBUST GEL-LIKE CLOT IN 30 SECONDS.
DYNAMIC APPLICATIONS
Granular presentation provides for the most diverse set of uses Works in hypothermic conditions FDA cleared to work on anti-coagulated blood No chemical exothermic reaction

Celox can stop even potentially lethal bleeding fast. It is easy to use (just pour, pack and apply pressure), very safe (tested to class 3 CE Mark standards) and extremely effective. When mixed with blood, Celox forms a robust gel-like clot in 30 seconds. When mixed with blood, Celox forms a robust gel-like clot in 30 seconds.It works independently of the bodys normal clotting processes. Celoxs clotting ability has been proven to work in the cold (hypothermia) or in the presence of common anticoagulants such as warfarin. It generates no heat and will not burn the casualty or care giver.
In pre-clinical tests by the US Navy, Celox was the only product to give 100% survival. It gave a strong stable MAP (mean arterial blood pressure) and was also the only product to give robust clotting with no rebleeding*. Celoxs safety has been tested to the intense class 3 CE mark standards. Celox is made with chitosan. Chitosan is made up of compounds of glucosamine, a sugar that is normally found in the body. Celox does NOT use non-degrading procoagulant minerals or nano particles such as smectite or kaolin, which will remain in the body indefinitely unless completely removed.

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