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Table Of Contents

Introduction
Epidemiology of gastrointestinal symptoms in diabetes
Prevalence of gastrointestinal symptoms in diabetes mellitus
Quality of life
References
Purposes and choices of diabetic animal models
Gastrointestinal function and the autonomic nervous system
Gastrointestinal functions disturbed in animal diabetes
Autonomic neuropathy in diabetic gastrointestinal dysfunction
Summary
Oesophageal Function
Normal oesophageal function and methods of investigation
Prevalence of abnormal oesophageal function in diabetes
Pathophysiology
Clinical manifestations
Diagnostic testing
Treatment
Prognosis
Gastric Function
Gastric motility in diabetes
Gastric secretion in diabetes
Gastric blood supply in diabetes
Clinical assessment of small intestinal and colonic function
Intraluminal digestion and nutrient absorption
Intestinal blood supply
Coeliac disease and diabetes mellitus
Anorectal Function
Physiology and pathophysiology
Effects of diabetes mellitus on anorectal function
Clinical assessment
Hepato-biliary and Pancreatic Function
The liver and diabetes
Causes of both diabetes and liver disease
Biliary system
Pancreas
Conclusions
Gut hormones and insulin secretion
Gut hormones in type 2 diabetes
Gut hormones in type 1 diabetes
Pharmacological influences
Evaluation of Gastrointestinal Autonomic Function
Evaluation of autonomic function
Vagal tests
The composite autonomic scoring scale
Conclusion
INDEX
P. 1
Gastrointestinal Function in Diabetes Mellitus

Gastrointestinal Function in Diabetes Mellitus

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Published by Wiley
Gastrointestinal function represents an important, and hitherto inappropriately neglected, aspect of diabetes management. Disordered gastrointestinal motor and sensory function occurs frequently in both type 1 and type 2 diabetes and may be associated with gastrointestinal symptoms that adversely affect quality of life.

During the last two decades there has been a rapid expansion in knowledge in this area. It is now recognised that upper gastrointestinal motility is pivotal to the regulation of postprandial blood glucose concentrations in both health and patients with diabetes. This book is the first of its kind and was stimulated by the need to consolidate these recent advances, which dictate that a knowledge of gastroenterology as it relates to diabetes is now required of the clinician/diabetologist.

Features an organ-specific overview of the epidemiology and pathophysiology of disordered gastrointestinal (including hepatobiliary and pancreatic) function in diabetes mellitusContains guidelines for the clinician, diabetologist and gastroenterologist for both diagnosis and managementIncludes a comprehensive description of the relation between gastrointestinal function, gastrointestinal hormones, autonomic nerve function and glycaemic control in animal modelsCovers the development of new treatment options, particularly those targeted at the reduction of postprandial hyperglycaemia, to optimise glycaemic control

This book will be of interest to gastroenterologists, diabetologists, specialist nurses and clinical researchers.

Gastrointestinal function represents an important, and hitherto inappropriately neglected, aspect of diabetes management. Disordered gastrointestinal motor and sensory function occurs frequently in both type 1 and type 2 diabetes and may be associated with gastrointestinal symptoms that adversely affect quality of life.

During the last two decades there has been a rapid expansion in knowledge in this area. It is now recognised that upper gastrointestinal motility is pivotal to the regulation of postprandial blood glucose concentrations in both health and patients with diabetes. This book is the first of its kind and was stimulated by the need to consolidate these recent advances, which dictate that a knowledge of gastroenterology as it relates to diabetes is now required of the clinician/diabetologist.

Features an organ-specific overview of the epidemiology and pathophysiology of disordered gastrointestinal (including hepatobiliary and pancreatic) function in diabetes mellitusContains guidelines for the clinician, diabetologist and gastroenterologist for both diagnosis and managementIncludes a comprehensive description of the relation between gastrointestinal function, gastrointestinal hormones, autonomic nerve function and glycaemic control in animal modelsCovers the development of new treatment options, particularly those targeted at the reduction of postprandial hyperglycaemia, to optimise glycaemic control

This book will be of interest to gastroenterologists, diabetologists, specialist nurses and clinical researchers.

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Publish date: Aug 13, 2004
Added to Scribd: Jun 05, 2013
Copyright:Traditional Copyright: All rights reservedISBN:9780470869642
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