Dr.

Maolin

Urinary tract

Urinary tract

2 kidneys 2 ureter 1 urinary bladder 1 urethra

Acid base balance Excrete waste product Maintain volume extracelluler fluid Endocrine function
Eritropoietin renin

Kidney function

Kidney
Retroperitoneal Length 10-12cm, width 5-6cm, AP 3-4cm Medial border : hillum

Renal sinus Renal pelvis

Nephrons (1,5-3 million)

Renal corpuscle Proximal convoluted tubule (PCT) Loop of henle Distal convoluted tubule (DCT)

Kidney

Uriniferous tubule
Nephrons Collecting tubule Collecting duct

Corteks
Renal corpuscle PCT and DCT Collecting tubule

Medulla
Loopof henle Collecting duct

Filtrate nephron composition (+ metabolic waste & selective reabsorb) collecting segment absorb water concentrate urine to papillary duct (duct of bellini)

Nephron
Renal corpuscle Prox. Convoluted Tubule (PCT) Loop of Henle Distal Convoluted Tubule (DCT) Collecting segment

Nephron::renal corpuscle

Bowman capsule : cup shape, expansion of PCT

Visceral layer (podocyte) Parietal layer

Glomerulus
Vascular pole Urinary pole

Podocyte

Podocytes
Pedicles (foot processes) Slit diafragma, consist of neprin space,

fx:filtration slit for water, glucose, as, amino, metabolic waste produt, no protein plasma

Basal lamina
Lamina rara eksterna Intermediate lamina densa Lamina rara interna

Sel mesangial : space between glomerular capillary, fx: fagosit, basal lamina turnover

Nephron::PCT
Cuboidal/lowcolumnar cell Brush border Apical canaliculi endocytosis macromolecule Absorb 85% water and salt, glucose, as.amino, excrete creatinine

Nephron::loop of Henle
Descending thick limb Descending thin limb, fx: pump NA and Cl, reabsorb 5% of water

Junction between desc thick limb n thin limb Brush border ends n cuboidal epithelium squamous epithelium, few microvilli.

Nephron::DCT
Cuboidal cell, short microvilli, no brush border, no apical canaliculi Specialized darker staining cell macula densa Fx: controlled by ADH absorb Na, secretes K, absorb 8% of water

Nephron::collecting segment
Principal cell (short microvilli) Intercalated cell, fx: acid base balance by reabsorb bicarbonate Controlled by ADH, absorb 4% of water

Juxtaglomerular complex
1. Specialized cell of macula densa DCT 2. JGC modifying smooth muscle cell of afferent arteriola 3. Mesangial cell Produce secretory granule renin

Blood supply
Renal artery lobar artery interlobar artery arcuate artery interlobular artery intralobular artery afferent arteriol efferent artriol vasa recta Vena : stellate vein interlobular vein arcuate vein interlobar vein renal vein

Renal pelvis and ureter

Trantitional epithel Muscle contraction : peristaltic waves

Urinary bladder
Mucosa : transtitional epithel Muscle layer

Outer : longitudinal Medial : circular/oblique Inner : longitudinal

Urethra
Above ejaculatory duct : transtitional epithel Distal ejaculatory duct : pseudostratified columnar Penile : stratified squamous epithel Women : stratified squamous epithel