Lithium overview, lithium monitoring andprotocol to help prevent toxicity
•Lithium discovered by Swedish Chemist – Johan Arfredsonin 1817.•Lithium is element no. 3 in the periodictable –a soft silvery metal.•Lithium is used as lithium salts includinglithium carbonate, lithium citrate andlithium orotate.
Lithium uses and origins
•Used as a mood stabilizer in the treatmentof bipolar disorder.•Lithium must be used carefully as thedosages used for the treatment in humansis only slightly lower than toxic amounts.•Blood levels should be carefullymonitored. Therapeutic levels rangebetween 0.4 to 0.8 mmol/l. Toxic rangeusually 1.5 mmol/l, but may begin at 1.0.