Why & How Swine flu is a major threat?

Swine flu was first identified in 1930 as acommon and sometimes fatal respiratorydisease in pigs caused by type A influenzavirus (H1N1). Human are said to haveinfected the pigs and now the virus hasreturned to infect humans. Influenza A (H1N1) virus resistance to oseltamivirwas reported by WHO in July 2008 and has spread all over the world. Theseantiviral treatment is expensive and does not kill the virus but reduce viralsheading and spreading. Some beleive the treatment may reduce infection if taken as prophylaxis. The treatment must be given as soon as the symptomsoccur but it is very difficult to diagnose clinically. Indiscriminate use will alsomake the virus develop resistance. The European Centre for Disease Prevention and Control said that the infection of humans with influenza 'A' virus of animal origins is a concern "because of the riskthat this could represent the appearance of viruses with pandemic potential." Swine and human H1N1 viruses arenot the same, which means thatseasonal flu vaccines for humanswill not work against the animalvariant. The impact of a newinfluenza pandemic has grossly beenestimated at 1-2 billion cases of flu,5-12 million cases of severe illness,and 1.5-3.5 million deathsworldwide. It could result in 1million to 2.3 million hospitalizationsand 250 000 to 650 000 deaths inindustrialized nations alone.Patients with Swine flu will have poor immune response to prevent bacterialinfections. This will help entry of CA-MRSA (colonised in our nostrils) through themucus membrane and spread rapidly to lung producing pneumonia. In hospitals,very sick patients will be subjected to practical procedures like IV drips andcatheter insertion. These devices will help MRSA enter circulation resulting ininvasive MRSA (severe septicaemia and death).HIV was taken seriously and not MRSAas a major threat in 1980s. In UK, MRSAwas rapidly spreading in neonatal units.Infected babies were not even isolatedand the callus attitude of nurses anddoctors helped these bacteria multiplyand spread. The first report of invasiveCA-MRSA was reported in USA wasreported in JAMA (2007 highlighted inCNN. Since then various countries havecome forward to accept they have aproblem. This bacteria has beenspreading their plasmid and educatingother bacteria to resist antibiotics. Nowwe have almost ten different bacteriaand fungus that are resistant totreatment.