Chapter 11The Endocrine SystemIntroductionA.The endocrine system is made up of the cells, tissues, and organs thatsecrete hormones into body fluidsB.The body has two kinds of glands, exocrine (secretes products intoducts) and endocrine (secretes products into body fluids)General Characteristics of the Endocrine SystemA.Endocrine glands and their hormones regulate a number of metabolicprocesses within cells, as well as reproduction, development, and growthB.Endocrine glands include the pituitary gland, thyroid gland, parathyroidglands, adrenal glands, pancreas, and other hormone excreting glandsand tissuesHormone ActionA.A hormone is a biochemical secreted by one cell that affects a specifictarget cell with appropriate cell surface receptorsB.Hormones are steroids, amines, peptides, proteins or glycoproteins; theycan influence target cells even if they are present only in minuteconcentrationsC.Prostaglandinsa.Prostaglandins are locally produced lipids that affect the organ inwhich they are producedb.Prostaglandins produce a variety of effects; some relax smoothmuscles, others contract smooth muscles, some stimulate secretionof other hormones, and others influence blood pressure andinflammationControl of Hormonal SecretionsA.Hormone levels are very precisely regulatedB.Negative feedback systemsa.Commonly, negative feedback mechanisms control hormonalreleasesb.In a negative feedback system, a gland is sensitive toconcentrations of the substance it regulates
c.
When the concentration of the regulated substance reaches acertain level (high or low), it inhabits the gland from secretingmore hormone until the concentration returns to normal (if thelevel is too high) or releases more (if the level is too low)
Leave a Comment