Everand Logo

Welcome to Everand!

  • Discover millions of ebooks, audiobooks, and so much more with a free trial

    Only $11.99/month after trial. Cancel anytime.

    Prediction of Protein Structures, Functions, and Interactions
    Prediction of Protein Structures, Functions, and Interactions
    Prediction of Protein Structures, Functions, and Interactions
    Ebook289 pages7 hours

    Prediction of Protein Structures, Functions, and Interactions

    By Janusz M. Bujnicki

    ()

    Read preview

    About this ebook

    The growing flood of new experimental data generated by genome sequencing has provided an impetus for the development of automated methods for predicting the functions of proteins that have been deduced by sequence analysis and lack experimental characterization.

    Prediction of Protein Structures, Functions and Interactions presents a comprehensive overview of methods for prediction of protein structure or function, with the emphasis on their availability and possibilities for their combined use. Methods of modeling of individual proteins, prediction of their interactions, and docking of complexes are put in the context of predicting gene ontology (biological process, molecular function, and cellular component) and discussed in the light of their contribution to the emerging field of systems biology. Topics covered include:

    • first steps of protein sequence analysis and structure prediction
    • automated prediction of protein function from sequence
    • template-based prediction of three-dimensional protein structures: fold-recognition and comparative modelling
    • template-free prediction of three-dimensional protein structures
    • quality assessment of protein models
    • prediction of molecular interactions: from small ligands to large protein complexes
    • macromolecular docking
    • integrating prediction of structure, function, and interactions

    Prediction of Protein Structures, Functions and Interactions focuses on the methods that have performed well in CASPs, and which are constantly developed and maintained, and are freely available to academic researchers either as web servers or programs for local installation. It is an essential guide to the newest, best methods for prediction of protein structure and functions, for researchers and advanced students working in structural bioinformatics, protein chemistry, structural biology and drug discovery.  

    LanguageEnglish
    PublisherWiley
    Release dateDec 23, 2008
    ISBN9780470741900
    Prediction of Protein Structures, Functions, and Interactions

    Related to Prediction of Protein Structures, Functions, and Interactions

    Related ebooks

    Biology For You

    View More
    View More

    Related podcast episodes

    Related articles

    • Article

      For Better Diagnosis, Watch Proteins Fold In Real-time

      Jun 10, 2018

      10A new method can examine protein assembly in real time, in living cells, to find problems in the process and diagnose the resulting diseases, according to new research. Proteins in the body need to be perfectly arranged, or folded, to do their jobs

      2 min read

    • Article

      New Way To Study Protein Complexes Doesn’t Break Them Up

      Mar 23, 2018

      Researchers have developed a new way to study protein complexes. Proteins are the worker bees of the cell, mainly ganging up to form macromolecular, multicomponent complexes to perform intricate cellular tasks. “Proteins are the main drivers of prett

      2 min read

    • Article

      Calling Embryo Editing ‘Premature,’ Russian Authorities Seek To Ease Fears Of A Scientist Going Rogue

      Oct 16, 2019

      The Russian health ministry’s stance puts at least a temporary hurdle in front of Denis Rebrikov's plan to edit the genome of a human embryo.

      6 min read

    • Article

      5 Screen-Time Tips for Children’s Sleep

      Nov 6, 2017

      In a new manuscript on digital media and sleep, researchers recommend removing electronic media from children’s bedrooms and encouraging calming bedtime routines to help kids sleep better. The manuscript is based on previous studies that suggest the

      1 min read

    • Article

      Scientists Control Tiny ‘Factories’ In Engineered Cells

      Mar 7, 2018

      Researchers have discovered how to dynamically manage the allocation of essential resources inside engineered cells. The research could advance the potential of synthetically programming cells to combat disease and produce new drugs. They developed a

      2 min read

    • Article

      Lights Within

      Feb 25, 2021

      Lights Within
      3 min read

    • Article

      ‘Failed Motors’ May Cause Rare Lung Disease

      Jan 29, 2018

      Researchers may have pinpointed the cause of a rare genetic lung disease. While most people recover from respiratory infections within a few weeks, for those with primary ciliary dyskinesia, the sniffling, coughing, and congestion never end. The tiny

      3 min read

    • Article

      How Bacteria In Your Gut Chow Down On Starch

      Feb 5, 2018

      Researchers know a little more about how bacteria in your gut breaks down some types of starch and turns them into nutrients your body can use. The findings, which appear in Biophysical Journal, will ultimately help doctors when they prescribe antibi

      2 min read

    • Article

      ‘Legos of Life’ Stack Together to Build Proteins

      Jan 23, 2018

      After smashing and dissecting nearly 10,000 proteins to understand their component parts, scientists have discovered the “Legos of life”—four core chemical structures that can be stacked together to build the myriad proteins inside every organism. Th

      2 min read

    Related categories

    Reviews for Prediction of Protein Structures, Functions, and Interactions

    0 ratings

    0 ratings0 reviews

    What did you think?

    Tap to rate

    Review must be at least 10 words

      Book preview

      Prediction of Protein Structures, Functions, and Interactions - Janusz M. Bujnicki

      Enjoying the preview?
      Page 1 of 1