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QuantitativeGenetics
Fundamental GeneticsLecture 6
John Donnie A. Ramos, Ph.D.
Dept. of Biological SciencesCollege of ScienceUniversity of Santo Tomas
Kinds of Heritable Traits
Qualitative Traits
with contrasting expressions
discontinuous traits
mostly controlled by a single gene
Quantitative Traits
continuous traits
controlled by multiple genes / polygenes(severalgenes located in different chromosomes but areresponsible for a single trait)
phenotypes in ranges
phenotypes show normal distribution curve (bell-shaped curve)
 
Quantitative Trait Examples
Height, skin color, intelligence
Follows a normal curve
Multiple Factor Hypothesis
Several factors or genes can causethe pattern of inheritance incontinuous traits
Cumulative
Quantitative
Inheritance of height in tobacco wasfirst studied by Josef GottliebKolreuter
 
Inheritance of Corolla Length
Performed by Edward East (1920)
Nicotiana longiflora 
Characteristics of Quantitative Traits
Quantifiable traits ( by measuring, weighing,counting, etc.)
Caused by 2 or more gene pairs in differentchromosomes
Each gene locus may be additive allele (contributioryallele) or non-additive allele (non-contributory allele)
Equal effects of each contributory allele
Presence of substantial phenotypic variation
 Analysis of polygenic traits requires the study of largenumbers of progeny from a population of organisms.
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