Small non-coding RNAs regulate gene expression, helping to control cellular metabolism, growth and differentiation. RNAi and related small-RNAmediated pathways have central roles in the silencing of gene expression in eukaryotic cells. At least 30% of human genes are thought to be regulated by microRNAs. Mutations in the genetic regions encoding the protein and / or RNA components of RNAi result in severe and sometimes lethal defects in cell growth and development.
Small non-coding RNAs regulate gene expression, helping to control cellular metabolism, growth and differentiation. RNAi and related small-RNAmediated pathways have central roles in the sile…