SINTEZA INSULINEI

HOMEOSTAZIA GLUCOZEI

Diabetul zaharat - diagnostic

Semnele clasice (poliurie, polidipsie,polifagie, scadere in greutate) si o glicemie 200mg/dl (in orice moment al zilei) Glicemie a jeun 126mg/dl, repetata de cel putin 2 ori, sugereaza, de asemenea, diabetul zaharat TTGO glicemia la 2h200mg/dl HbA1c 6.7% - e sugestiva pt DZ

Caracteristicile DZ
Caracteristici Varsta Diabet zaharat tip1 Diabet zaharat tip 2

Copii, adolescenti

Adulti, varstnici

Debutul
Scaderea in greutate cetoacidoza Insulinemia Istoric familial de DZ

Acut (cel mai frecvent)

frecventa frecventa Scazuta sau abenta rar DR3, DR4

silentios
inconstanta inconstanta Normala sau crescuta frecvent

Asociere HLA

Markeri de urmarire a DZ

Glicemia, TTGO Lipide si lipoproteine (CT, TG, HDL-C, LDL-C, apoA, apoB) HbA1 Albuminuria Corpi cetonici Autoanticorpi