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Acute Renal FailureAcute Renal Failure
Qiu boQiu boMay, 2009May, 2009
 
 
General considerationsGeneral considerations
Rapid decline in the GFR over days toRapid decline in the GFR over days toweeks.weeks.
Inability to maintain fluid andInability to maintain fluid andelectrolyte and to excreteelectrolyte and to excretenitrogenous wastesnitrogenous wastes
Cr increases by 88.4-132.6umol/LCr increases by 88.4-132.6umol/Ldailydaily
GFR <10mL/min, or <25% of normalGFR <10mL/min, or <25% of normal
 
 
DefinitionsDefinitions
Anuria: urine<100ml/dAnuria: urine<100ml/dOliguria: urine<400 mL/dOliguria: urine<400 mL/dAzotemia: Incr Cr, BUNAzotemia: Incr Cr, BUN
May be prerenal, renal, postrenalMay be prerenal, renal, postrenalChronic Renal InsufficiencyChronic Renal Insufficiency
Deterioration over months-yearsDeterioration over months-years
GFR 10-20 mL/min, or 20-50% of GFR 10-20 mL/min, or 20-50% of normalnormalESRD = GFR <5% of normalESRD = GFR <5% of normal
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