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•Smooth pursuit is of minor clinic diagnosticuse:
–Results are usually nonspecific–Affected by attention,–Difficulty getting norms and comparing acrosslabs and equipment due to different paradigms–Affected by ability to see and quality of target–Affected by medications–Declines with age–Worse in women
Pursuit
 
•Pursuit gain:–ratio of eye velocity to target velocity•affected by target velocity, accelerationand frequency–In a sinusoidal pursuit stimulus, thesethree things are interdependent–In a triangular wave pursuit stimulus;» velocity is constant»acceleration appears as periodicpulses» frequency and velocity can bevaried independently of acceleration» perfect tracking of the triangularwave stimulus is impossible becauseof the abrupt accelerations at turn-around time.
Pursuit
 
•Low Gain Pursuit Abnormalities:–Low steady-state pursuit gain (target ismaintaining the same speed and patientcannot maintain that eye speed: thus lowgain)•Old age•Parkinson’s disease•PSP•Cerebellar disorders•Hepatic encephalopathy (hepatoencephalopathy)•Following large cerebral lesions
Disorders of Smooth Pursuit
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