BIMM 110 Molecular Basis of Human Disease
TA: George Chengtchen@ucsd.eduOH: Tu 12:30-1:30 Sierra Summit or by appointmentSection: W 4:00-4:50 Center 203
Problem Set 8
Please email me if you have any suggestions for how to organize the final section.
This problem set covers lecture 14 and 15.1. What is the molecular mechanism by which Gleevec acts on treating Chronic MyelogenousLeukemia? Why is this treatment usually done late in the leukemia's development?2. A Ras mutation causes what events to occur at the cellular level?3. In what situation(s) would it be appropriate to treat a patient with Decitabine?4. Describe how GTP-dependent proteins are activated or inactivated.5. How is Myc overexpressed in Burkitt's Lymphoma? What are the normal functions of Myc?