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Simple Colloid Goitre

Simple Colloid Goitre



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Published by Aditya Pathak

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Published by: Aditya Pathak on May 22, 2009
Copyright:Attribution Non-commercial


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Simple Colloid Goitre
Goitre is defined as thyroidenlargement caused bycompensatory hyperplasia andhypertrophy of follicular epithelialresponse to Thyroid hormonedeficiency.
Two morphological forms of goitre are distinguished,
 –Simple or colloid goitre. –Nodular goitre.Etiopathogenesis
The presence of goitre reflectsimpaired synthesis of thyroid hormone,most often due to dietary deficiency of iodine. Impairment of thyroid hormonesynthesis leads to a compensatory risein serum TSH level which in turncauses hypertrophy and hyperplasia of thyroid follicular cells, which ultimatelycauses gross enlargement of thyroid.

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