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21_pharmacokinetics_pharmacodynamics

21_pharmacokinetics_pharmacodynamics

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Published by: SUTHAN on May 30, 2009
Copyright:Attribution Non-commercial

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05/11/2014

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Clinical Pharmacokinetics and
Pharmacodynamics
Janice E. Sullivan, M.D.
Brian Yarberry, Pharm.D.
Why Study Pharmacokinetics (PK)
and Pharmacodynamics (PD)?
\u2022Individualize patient drug therapy
\u2022Monitor medications with a narrow
therapeutic index

\u2022Decrease the risk of adverse effects while
maximizing pharmacologic response of
medications

\u2022Evaluate PK/PD as a diagnostic tool for
underlying disease states
Clinical Pharmacokinetics

\u2022The science of the rate of movement of
drugs within biological systems, as affected
by the absorption, distribution, metabolism,
and elimination of medications

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