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Awadu 1996

Awadu 1996

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Scientists with the support of the Centers of Disease Control (CDC) and World Health Organization (WHO) wanted to design a vaccine that could target infant populations aging between 5 to 9 months of age. Mothers who have natural immunity can effectively pass their maternal antibodies to their offspring without any breastfeeding giving disease protection up to 5 months of age (Black et al, 1986). In developing countries where measles mortality is high due to malnutrition and lack of adequate health care the CDC and WHO thought there was a need to construct a vaccine with a very high titer reach to this susceptible population. This vaccine was called the Edmonston-Zagreb (EZ-HT) strain. This EZ-HT measles vaccine ultimately proved to be deadly and was experimentally used on Mexican and Gambian babies 4 to 6 months old (Whittle et al, 1988). EZ- HT was experimental used on babies in Guinea-Bissau (Aaby et al, 1998). Experiments also took place in Senegal (Garenne et al, 1991). The Edmonston-Zagreb strain was also experimentally given to babies in Togo, Haiti and in the United States to impoverished minority communities in Los Angeles, California
Scientists with the support of the Centers of Disease Control (CDC) and World Health Organization (WHO) wanted to design a vaccine that could target infant populations aging between 5 to 9 months of age. Mothers who have natural immunity can effectively pass their maternal antibodies to their offspring without any breastfeeding giving disease protection up to 5 months of age (Black et al, 1986). In developing countries where measles mortality is high due to malnutrition and lack of adequate health care the CDC and WHO thought there was a need to construct a vaccine with a very high titer reach to this susceptible population. This vaccine was called the Edmonston-Zagreb (EZ-HT) strain. This EZ-HT measles vaccine ultimately proved to be deadly and was experimentally used on Mexican and Gambian babies 4 to 6 months old (Whittle et al, 1988). EZ- HT was experimental used on babies in Guinea-Bissau (Aaby et al, 1998). Experiments also took place in Senegal (Garenne et al, 1991). The Edmonston-Zagreb strain was also experimentally given to babies in Togo, Haiti and in the United States to impoverished minority communities in Los Angeles, California

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Published by: Heather Rhodes White on Aug 14, 2013
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03/10/2014

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