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Ghid Astm bronsic

Ghid Astm bronsic

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Published by Leonard D
Cursul de farmacologie clinica
Spitalul Grigore Alexandrescu
UMF "Carol Davila"
Cursul de farmacologie clinica
Spitalul Grigore Alexandrescu
UMF "Carol Davila"

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Published by: Leonard D on Jun 07, 2009
Copyright:Attribution Non-commercial

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05/11/2014

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National Heart, Lung andBlood InstituteExpert Panel 3Guidelines for Diagnosis andManagement of Asthma
 
 
Medications for asthma are categorized into two general classes:
KEY POINTS - MedicationKEY POINTS - Medication
1.long-term control medications used to achieve and maintaincontrol of persistent asthma2. quick-relief medications used to treat acute symptoms andexacerbations
 
 
Immunomodulators:
 
Omalizumab (anti-IgE) is a monoclonal antibody that prevents binding of IgE tothe high-affinity receptors on basophils and mast cells.Omalizumab is used as adjunctive therapy for 
 patients >12 years of age whohave allergies and severe persistent asthma (Evidence B).
Clinicians who administer omalizumab should be prepared and equipped to identify and treat anaphylaxis that mayoccur.
Long-term control medications
(listed in alphabetical order)
Corticosteroids:
They are
the most potent and effective anti-inflammatory medicationcurrently available (Evidence A)
.
Cromolyn sodium and nedocromil:
 
They are used as alternative,
but not preferred 
, medication for the treatment of mild persistent asthma
(Evidence A)
.They can also be used as preventive treatment prior to exercise or unavoidableexposure to known allergens.

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