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A Pathognomonic Signs

A Pathognomonic Signs

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Published by Nikhil Kumar Singh
Pathognomonic signs
Pathognomonic signs

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Published by: Nikhil Kumar Singh on Aug 26, 2013
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06/19/2014

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Pathognomonic
 A pathognomonicsignis a particular sign whose presence means that a particular disease is present beyond any doubt. Labelling a signor symptom"pathognomonic" represents a marked intensification of a "diagnostic" sign or symptom.The word is an adjective of Greekorigin derived from
 páthos
 
(meaning "disease") and gnōmon (meaning "judge").
 
Very few of the examples here are pathognomonic in the true sense of the word. For example, Parkinsonism is not only seen inParkinson's disease.
Disease Sign
Erythema chronicum migransInclusion body myositisFilamentous material seen in inclusion bodies under electron microscopyHypocalcemiaTrousseau signandChvostek sign TetanusRisus sardonicus
Bulimia NervosaChipmunk facies (parotid gland swelling) (Chipmunk facies also seen in marrow expansion secondary to
 
Disease Sign
Leonine facies(thickened lion-like facial skin) (Lionine facies also seen in Paget Disease of bone) So it isn'tpathognomonic.Measles
DiphtheriaPseudomembrane on tonsils, pharynx and nasal cavityChronic hemorrhagicpancreatitisGrey-Turner's sign(ecchymosis in flank area)CholeraRice-watery stool;not pathognomonic, also seen in mercury poisoningEnteric fever Rose spotsin abdomenMeningitisKernig's signandBrudzinski's sign CholecystitisMurphy's sign(pain on deep inspiration when inflamed gallbladder is palpated); also seen on abdominal trauma,
 
Disease Sign
surgery, etc Angina pectorisLevine's sign(hand clutching of chest); also seen in gastritis, etc.Patent ductus arteriosus
Machine-like murmur Pleural EffusionStony-dull percussion; also in any solid chest massesParkinson's disease

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