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U S007135195B 2
(1 2 )
U n ite d S ta te sP a te n t
H o lla d a y e t a l.
(1 0 )
P a te n tN o .:
(4 5 )
D a teo f P a te n t:
U S7 ,1 3 5 ,1 9 5 B 2
Nov. 14,2006
(5 4 )
TREATM ENTO FHUM ANSW IT H
C O L L O ID A LS IL V E RC O M P O S IT IO N
(7 3 )
A ssignee:
A m ericanS ilv e r,L L C , A lp in e , U T
(U S )
(7 5 )
In v e n to rs:
R o b e rtJ .H o lla d a y , L o g a n , U T
(U S );
H erbertC hristensen,A lp in e , U T
(U S );
W illiam
D . M o e lle r, A lp in e , U T
(U S )
A 6 1 P1 5 /0 2
(2 0 0 6 .0 1 )
A 6 1 P1 7 /0 0
(2 0 0 6 .0 1 )
A 6 1 P3 1 /0 0
(2 0 0 6 .0 1 )
A 6 1 P3 1 /0 2
(2 0 0 6 .0 1 )
A 6 1 P3 1 /0 4
(2 0 0 6 .0 1 )
A 6 1 P3 1 /1 0
(2 0 0 6 .0 1 )
(5 2 )
U .S . C l.

4 2 4 /6 1 8 ; 4 2 4 /4 0 5 ; 4 2 4 /4 8 9 ; 4 2 4 /4 9 0 ; 4 2 4 /6 1 6 ; 5 1 4 /8 4 9 ; 5 1 4 /8 5 8 ; 5 1 4 /8 9 4 ; 5 1 4 /8 9 5 ; 5 1 4 /9 2 4 ; 5 1 4 /9 3 1 ; 5 1 4 /9 3 2 ; 5 1 4 /9 3 4 ;

5 1 4 /9 5 1
(5 8 )
F ie ldo fC la ssific a tio nS e a r c h
4 2 4 /6 1 8 ,
4 2 4 /4 0 5 ,4 8 9 ,4 9 0 ,6 1 6 ;
5 1 4 /8 4 9 ,8 5 8 ,8 9 4 ,
5 1 4 /8 9 5 ,9 2 4 ,9 3 1 ,9 3 2 ,9 3 4 ,9 5 1
S e e a p p lic a tio n file fo r c o m p le te s e a rc h h is to ry .
R eferencesC ite d
(5 6 )
U .S . P A T E N T D O C U M E N T S
A ug. 15, 2003

S u b je c t to a n y d is c la im e r, th ete n no fth is p a te n tise x te n d e do r a d ju s te d u n d e r 3 5 U .S .c .154(b) by 409 days.

(2 1 )
A p p l. N o .: 1 0 /6 4 1 ,9 3 8
(* )
N o tic e :
(2 2 )
F ile d :
H o lla d a y e t al.
4 2 2 /1 8 6 .2 1
H o lla d a y e t al.
2 0 5 /3 4 1
A rata
5 1 4 /4 9 5
B urrell et al.
4 2 4 /6 1 8
Y a n e t a l.
4 2 4 /6 1 8
Y a n e t a l.
4 2 4 /4 8 4
4 /2 0 0 1
6 /2 0 0 4
5 /2 0 0 5
9 /2 0 0 5
5 /2 0 0 2
1 0 /2 0 0 3
6 ,2 1 4 ,2 9 9
B 1*
6 ,7 4 3 ,3 4 8
B 1*
6 ,8 9 0 ,9 5 3
B 1*
6 ,9 3 9 ,5 6 8
B 1*
2 0 0 2 /0 0 5 1 8 2 3
A l*
2 0 0 3 /0 1 8 5 8 8 9
A l*
*c ite d b y e x a m in e r
P rim a ryE xam iner-JohnP ak
(7 4 ) A tto r n e y , A g e n t,o rF irm -L iner,Y a n k e le v itz , S u n s h in e
&
R e g e n s tre if L L P
M ar. 24, 2005
P rio rP u b lic a tio nD ata
U S 2 0 0 5 /0 0 6 1 6 7 8A l
R e la te dU .S . A p p lic a tio nD ata
C o n tin u a tio n -in -p a rto f a p p lic a tio n N o . 0 9 /9 4 6 ,8 3 4 ,
f i l e do nSep.4 , 2001, now

P a t. N o . 6 ,7 4 3 ,3 4 8 , w h ic h isa c o n tin u a tio no f a p p lic a tio n N o . 0 9 /3 2 3 ,3 1 0 , file d o nJun.1 , 1999, now

P a t. N o . 6 ,2 1 4 ,2 9 9 .
(6 0 )
P ro v is io n a l a p p lic a tio n N o . 6 0 /4 7 5 ,6 5 7 , file do nJ u n .
3 ,2 0 0 3 .
(6 5 )
(6 3 )
1 4 C la im s , N o D ra w in g s
W ed is c lo s e a c o lo rle s s c o m p o s itio n c o m p ris in g s ilv e r p a r\ue000
ticles and w ater, w herein said particles com prise an interior
o fe le m e n ta l s ilv e r a n d
a n
e x te rio ro f io n ic
s ilv e r o x id e ,
w h e re in th e s ilv e r p a rtic le s a re p re s e n t in th e w a te r a t a le v e l
o fa b o u t5 -4 0 p p m , a n d w h e re in th e c o m p o s itio n m a n ife s ts
s ig n ific a n t a n tim ic ro b ia l p ro p e rtie s . M e th o d so fu se o fth e
c o m p o s itio n a re d e s c rib e d .
(5 1 )
In t.C l.
A 6 1 K3 3 /3 8

A 6 1 K3 3 /4 0
A 6 1 K9 /1 0
A 6 1 K9 /1 4

A 0 1 N2 5 /1 2
A 0 1 N2 5 /2 6
A 0 1 N5 9 /1 6
A 0 1 N5 9 /0 0

A 6 1 P1 1 /0 0 A 6 1 P1 3 /0 0 A 6 1 P1 5 /0 0

(2 0 0 6 .0 1 )

(2 0 0 6 .0 1 ) (2 0 0 6 .0 1 ) (2 0 0 6 .0 1 )

(2 0 0 6 .0 1 )
(2 0 0 6 .0 1 )
(2 0 0 6 .0 1 )
(2 0 0 6 .0 1 )

(2 0 0 6 .0 1 ) (2 0 0 6 .0 1 ) (2 0 0 6 .0 1 )

(5 7 )
A B S T R A C T
U S
7 ,1 3 5 ,1 9 5B 2
2
D E T A IL E D
D E S C R IP T IO N
OF THE
IN V E N T IO N
T he
fo llo w in g
d e s c rip tio n
i s
p ro v id e d
t o
e n a b le
a n y
p e rs o n s k ille d in th e a rt to m a k e a n d u s e th e in v e n tio n a n d
A
p re fe rre d
e m b o d im e n t
o f
th e
p r e s e n t
in v e n tio n
i s
d ire c te d to
c o m p o s itio n so fs ilv e ri n w a te r m a d e u s in g
a

m o d ific a tio no fth e d e v ic e a n d m e th o d s d e s c rib e di n U .S . P a t. N o . 6 ,2 1 4 ,2 9 9 , w h ic h is a p a r e n to fth e in s ta n t a p p li\ue000 c a tio n a n d is in c o rp o ra te d h e re inb yr e f e r e n c e .

The device and processo fP a t. N o . 6 ,2 1 4 ,2 9 9 h a v e b e e n m o d ifie d a n d im p ro v e d to p ro v id e th e s ilv e r c o m p o s itio no f th e p re s e n t in v e n tio n . E s s e n tia lly , th e e ig h t-s ilv e r/o n e c o m \ue000 m on

e le c tro d e d e v ic e
a s
d is c lo s e d
i nth e p a te n t h a s
b e e n
1 0

m o d ifie d a n d s c a le d to fit a 7 5 -g a llo n w a te r c h a m b e r.T o s ta rt th e p ro c e s s a p p ro x im a te ly 7 0 g a llo n so fh ig h p u rity w a te r a re p la c e di nth e c h a m b e r.T o th is is a d d e d a p p ro x im a te ly fiv e

g a llo n s
o f
s ilv e r
c o m p o s itio n
p r o d u c e d
i n
a
p rio r
p ro d u c tio n ru n . T h is is n e c e s s a ry
b e c a u s e th e h ig h p u rity
1 5
w a te r is in s u ffic ie n tly c o n d u c tiv e fo r th e p ro c e s s to

o c c u r p ro p e rly . T h e w a te r c h a m b e r is e q u ip p e d w itha na ir in p u t th a t a llo w s a s tre a m

o fa ir b u b b le s tob e s tre a m e d th ro u g h
th e liq u id d u rin g th e p ro c e s s in g .I thas been discovered that
th is
a p p r o a c h
g iv e s im p ro v e d m ix in g
a s
c o m p a r e d to
th e
2 0
im p e lle r m ix e r d e s c rib e d in th e p a te n t.
T he
e le c tro d e
d e v ic e
is
o p e ra te d
a t a p p ro x im a te ly
te n
th o u s a n d v o lts a lte rn a tin g c u rre n t (w ith e a c h s ilv e r e le c tro d e
h a v in g
a n
in d iv id u a l v o lta g e
supply) as
d e s c r ib e d
i n
th e
p a te n t.I th a s b e e n fo u n d th a t v o lta g e s s ig n ific a n tly lo w e r
2 5
th a n
th is
p ro d u c e
a c o m p o s itio n w ith
la rg e r p a rtic le s n o t
h a v in g
th e
o p tim a l
p ro p e rtie s
d e s c r ib e d
h e re in .

V o lta g e s s ig n ific a n tly h ig h e r te n d to p ro d u c e a s o lu tio n w ith s ig n ifi\ue000 c a n t io n ic s ilv e r d is s o lv e d th e re in . T h e p re s e n t c o m p o s itio n com prisesi ne x c e s so f 9 7 %

m etallic silv er w ith essen tially
3 0
n o fre e io n ic s ilv e ri n s o lu tio n .
T h e s ilv e r c o n c e n tra tio n is d e te rm in e d a c c o rd in g to

th e m e th o d s e x p la in e d b e lo w . E s s e n tia lly , th e d e v ic e is o p e r a te d c o n tin u o u s ly

a n d
sam ples
a re
a n a ly z e d
u n til
th e
d e s ir e d
s ilv e r c o n c e n tra tio n
is
a tta in e d . T h e
1 0
p p m
c o m p o s itio n
3 5

re q u ire s a p p ro x im a te ly o n e a n d o n eh a lf d a y so f o p e ra tio n . T h e 2 2 p p m s o lu tio n re q u ire s a p p ro x im a te ly th re e d a y s, a n d th e 3 2

p p m
c o m p o s itio n re q u ire s a p p ro x im a te ly
s ix
d a y s .
T he
r a t e
o fth e
p r o c e s s
a p p e a r s
t o
s lo w
a s
th e
h ig h e r
c o n c e n tra tio n s
a re
a tta in e d .
H ig h e r c o n c e n tra tio n s
ta k e
a
4 0

p ro h ib itiv e ly lo n g tim e w ith th e u ltim a te h ig h e s t c o n c e n tra \ue000 tio n b e in g a b o u t 5 0 p p m , a t le a s t w ith in th e c u rre n t p a ra m \ue000 e te r s .

T he
c o m p o s itio n s
a ll
h a v e
th e
s iz e
c h a ra c te ris tic s
d e s c r ib e d
b e lo w
a n d
u n lik e
c o n v e n tio n a l s ilv e r c o m p o s i\ue000
4 5
tio n s a re c o m p le te ly c o lo rle s s a n d s ta b le to

lig h t a n d te m \ue000 perature changes w ithout useo fa n y a d d itiv e s . T h e c o m p o \ue000 s itio n s a re u n re a c tiv e to w a rd s a d d e d h y d ro g e n p e ro x id e .

H ydrogen peroxide, a know
d is in fe c tin g a g e n t, h a s b e e n
fo u n d to
h a v e a s y n e rg is tic
interaction w ith the
in v e n tiv e
5 0
s ilv e r c o m p o s itio n . H y d ro g e n p e ro x id e is a v a ila b lei n c o n \ue000
c e n tra tio no f3 0 %
w g h t/v (%

w e ig h t p e r v o lu m eo r w e ig h t p e rc e n t)o rh ig h e r. A lth o u g h th e h ig h e r c o n c e n tra tio n s a re usable, the preferred concentrations arei nth e ra n g eo f I to 5 %

w g h t/v .
A
p re fe rre d
e m b o d im e n t
o f
th e
p r e s e n t
in v e n tio n
i s
d ire c te d to c o m p o s itio n s c o m p ris in g 5 to 4 0p p msilver, said
s ilv e r
b e in g
p rim arily
e le m e n ta l
s i l v e r ,
I
t o
3
w ght
%
hydrogen peroxide, and w ater. A
p re fe rre d e m b o d im e n to f
th e
p re s e n t in v e n tio n
is
th e
u s e ,
a n d
m e th o d
o fu s e ,
o f
6 0
c o m p o s itio n s c o m p ris in g
10 to
4 0
p p m
s ilv e r a n d
I
t o
3
w ght %
h y d ro g e n p e ro x id ei nw a te r a s a n tim ic ro b ia l a g e n ts .
A R E AOF THE ART
S U M M A R Y O F T H E IN V E N T IO N
D E S C R IP T IO N
O F T H E P R IO R A R T
1
T R E A T M E N T O F H U M A N S W IT H
C O L L O ID A L S IL V E R
C O M P O S IT IO N

T h e p re s e n t in v e n tio n is g e n e ra lly d ire c te d to th e u s eo f silver, at a levelo f 5 to 4 0 p p m in w ater, to killo r to disable m icroorganism s w hich are hazardous to hum an beings. T he p re s e n t in v e n tio n

s p e c ific a lly
is
d ire c te d
t o
c o m p o s itio n s
c o m p ris in g
s ilv e r
p a rtic le s ,
s a id
p a rtic le s
c o m p ris in g
a n
5 5
in te rio ro f e le m e n ta l s ilv e r a n da n e x te rio ro f io n ic
s ilv e r

o x id e , a n d w a te r, w h e re in th e s ilv e r p a rtic le s a re p la c e di n c o llo id a l s u s p e n s io n in th e w a te r a t a le v e lo f5 -4 0p p m to ta l s i l v e r .A ne m b o d im e n to f th e p re s e n t in v e n tio n c o m p ris e s s ilv e r p a rtic le s in w a te r, a t a c o n c e n tra tio n

o f5 -4 0
ppm ,
w h e re in
m ore
th a n
5 0 %
o fth e
s ilv e r
p a rtic le s
h a v e
a
m a x im u m
d im e n s io n
le s s
th a n
0 .0 1 5
m icrom eters.
T he
c o m p o s itio n
o f
s ilv e r
i n
w a te r
o f
th is
in v e n tio n
is
a n
e ffe c tiv e a n tim ic ro b ia l a g e n t. T h is in v e n tio n is d ire c te d to
s ilv e r c o m p o s itio n s ,o f5 -4 0p p m
silv er in w ater, w h ic h are
6 5
e ffe c tiv e a n tim ic ro b ia l a g e n ts , a n d to m e th o d so f u s in g s a id
s ilv e r c o m p o s itio n s as a n tim ic ro b ia l a g e n ts .
T h e p re s e n t in v e n tio n g e n e ra lly re la te s to c o llo id a l silv e r,
and m ore particularly to

a c o m p o s itio no fc o llo id a l s ilv e r a n d a m e th o d fo r u s in g s a id c o m p o s itio n a s a n a g e n t a g a in s t o rg a n is m s h a rm fu l to th e h e a ltho fhum ans.

T h e p re s e n t a p p lic a tio n is a c o n tin u a tio n -in -p a rto fa p p li\ue000 c a tio n S e r. N o . 0 9 /9 4 6 ,8 3 4 , file d S e p . 4 , 2 0 0 1 , n o w U .S P a t. 6 ,7 4 3 ,3 4 8

w h ic h is a c o n tin u a tio no fa p p lic a tio n S e r. N o . 0 9 /3 2 3 ,3 1 0 , file d Ju n .I ,1 9 9 9 , n o w U .S . P a t. N o . 6 ,2 1 4 ,2 9 9 . T h e p re s e n t a p p lic a tio n c la im s p rio rity to p ro v is io n a l a p p li\ue000 c a tio n 6 0 /4 7 5 ,6 5 7 , file d Ju n . 3 , 2 0 0 3 , a n d in c o rp o ra te db y reference herein.

I tis w e ll k n o w n th a t c e rta in p re p a ra tio n so f s ilv e r h a v e

g e rm ic id a l p ro p e rtie s . S ilv e r w a s e m p lo y e d a s a g e rm ic id e a n d a n a n tib io tic b e fo re m o d e r n a n tib io tic s w e r e d e v e lo p e d . I np re v io u s c e n tu rie s , u s e rs w o u ld s h a v e s ilv e r p a rtic le s in to th e ir d rin k in g w a te r,o rs u b m e rg e w h o le s ilv e r p ie c e si n th e d rin k in g

water, for the purposeo fin g e s tin g th e

s ilv e rb y d rin k in g th e w a te r.I t s e e m s lik e ly th a t th e p ra c tic eo f e a tin g w ith silv er u ten sils (i.e., silv erw are) resu lted fro m

a b e lie fi n
th e h e a lth fu l p ro p e rtie so f silv e r.
T h e r e
m ay
b e
m any
r e a s o n s
w hy
a d m in is te rin g
s ilv e r
s u s p e n d e d in s o lu tio n w o u ld e n h a n c e a n in d iv id u a l's h e a lth .
I tis
p o s s ib le th a t s u c h
a
s o lu tio n
o p e ra te s to

in h ib it th e g ro w tho fbacteria, viruses, and other unw anted organism s, a s w e ll a s e ra d ic a tin g

s u c h e x is tin g

bacteria, viruses, and other organism s.I tis also possible that a solutiono f silver can have

a n
an ti-in flam m ato ry
e ffe c t,
sufficient to
r e d u c e
s y m p to m so fasthm a.
The present invention describes the useo fa s ilv e r c o m \ue000
p o s itio n
i n
w a te r
t o
tre a t
c e rta in
hum an
ailm en ts.
A n
e m b o d im e n to f th e in v e n tio n is a s ilv e r c o m p o s itio n c o m \ue000
prising sm all particleso fs ilv e r w h ic h c o m p ris e a n in te rio r
o fm etallic
s ilv e r
a n d
a n
e x te rio r
o fio n ic
s ilv e r
w h ic h

particles are suspended in w ater. A preferred em bodim ento f th e in v e n tio n is a s ilv e r c o m p o s itio n c o m p ris in g p a rtic le so f s ilv e r w h e re in m o re th a n 5 0 %

o fth e n u m b e r o fp a rtic le s a re
le s s
th a n
0 .0 1 5
m icrom eters
i n
s iz e
a n d
th e
p a rtic le s
a re
c o llo id a lly s u s p e n d e d in w a te r.
U S
7 ,1 3 5 ,1 9 5
B 2
3
4
EX A M PLES
I .F o rm a tio no f C o m p o s itio n

C o m p o s itio n so fs ilv e r in w a te r c a nb e m a d e a c c o rd in g to p ro c e d u re s se t fo rthi nU .S . P a t. N o . 6 ,2 1 4 ,2 9 9 , in c o r p o r a te d b yre fe re n c e h e re w ith .

A
p re fe rre d m e th o d
fo r p ro d u c in g
a
c o m p o s itio n

com \ue000 p ris in g s ilv e r a c c o rd in g to th is in v e n tio n u tiliz e s a e le c tro \ue000 c h e m ic a l c e ll c o m p ris in g e le c tro d e s a n d c o m p ris e s th e s te p s

(a ) p la c in g a s ilv e r e le c tro d e in c o n ta c t w ith a q u a n tityo f
high purity w ater;
(b ) c o n v e y in g
e le c tric a l c u rre n t th ro u g h th e s ilv e r e le c \ue000
tro d e to th e re b y s e p a ra te p a rtic le so fsilver from
said silver
e le c tro d e
i n
a
m anner
sufficient to
c a u s e
p ro d u c tio n
o f
s u s p e n d e d s ilv e r p a rtic le s w ith in th e w a te r; a n d
(c )
a g ita tin g
th e
w a te r d u rin g
s a id
p ro d u c tio n
o fs u s \ue000
p e n d e d s ilv e r p a rtic le s to th e re b y d is p e rs e th e s ilv e r p a rtic le s
in to
a m o re u n ifo n n
c o n c e n tra tio n w ith in s a id w a te r s u c h
th a t a h ig h e r q u a n tity
o fs u s p e n d e d s ilv e r p a rtic le s c a nb e
produced per batch.
A n o th e r p re fe rre d m e th o d fo r p ro d u c in g

a c o m p o s itio n c o m p ris in g s ilv e r u tiliz e sa ne le c tro c h e m ic a l c e ll a n d c o m \ue000 prises the steps of:

(a) establishinga ne le c tric a l c irc u it c o m p ris in g a c u rre n t
s o u rc e , a n d a first c o n d u c to r e le c tric a lly c o n n e c te d to

s a id c u rre n t s o u rc e a n d a s e c o n d c o n d u c to r e le c tric a lly c o n n e c te d t o

said current source, w herein said first conductor is dis\ue000 posed spaced apart from said second conductor, and w herein at least oneo fth e c o n d u c to rs is m a d e o fe le m e n ta l s ilv e r;

(b ) c lo s in g th e c irc u itb yp la c in g th e first c o n d u c to r a n d th e s e c o n d c o n d u c to ri nco m m u n icatio n w ith a fluidic resis- to r;

(c )
o p e ra tin g
th e
c u r r e n t
s o u rc e
t o
s u p p ly

a lte rn a tin g c u rre n t s im u lta n e o u s ly to th e first c o n d u c to r a n d th e s e c o n d conductor such

th a t v o lta g e
is
in c re a s in g
a n d
d e c r e a s in g
w ith in th e first a n d s e c o n d c o n d u c to rs in a lte rn a tin g ta n d e m
6 0
t o
th e re b y
c a u s e
s ilv e r p a rtic le s to
separate from
th e
f ir s t
e le c tro d e a n d e n te r th e flu id ic re s is to r a n d b e c o m e d is p o s e d
in suspension w ithin said fluidic resistor; and
(d ) s e le c tiv e ly a d ju s tin g th e e le c tro d e sb ym o v in g th e m
to w ard
th e
flu id ic
resistor to
com pensate
for decrease
i n
e le c tro d e le n g th d u e to g ra d u a l s e p a ra tio no fs ilv e r p a rtic le s
th e re fro m to th e re b y p re v e n t a rc in g fro m
o c c u rrin g b e tw e e n
the electrodes and said fluidic resistor.
3 5
A
fu rth e r
c la s s
o fe m b o d im e n ts
is
a n y
o fth e
a b o v e \ue000
d e s c r ib e d
c o m p o s itio n s , w h e re in th e

s ilv e r p a rtic le s c o m \ue000 prise both silveri nth e z e ro -v a le n t, th a t is, m e ta llic , o x id a \ue000 tio n

s ta te
[A g (O )]
a n d
a
c o a tin g
o f
s ilv e r
i n
a n
io n ic
o x id a tio n
s e le c te d
fro m
th e
g ro u p
c o n s is tin g
o fA g (I) ,
A g(II), and A g(III).
A
fu rth e r
c la s s
o fe m b o d im e n ts
is
a n y
o fth e
a b o v e -
d e s c r ib e d
c o m p o s itio n s , w h e re in th e

s ilv e r p a rtic le s c o m \ue000 prise b o th silveri nth e z e ro v a le n t, th a t is m e ta llic , o x id a tio n state [A g(O )] and a coatingo fs ilv e r o x id e w ith th e s to ic h i\ue000 om etry A gO .

E x p e rim e n ta l e v id e n c e s h o w s th a t A g O in th e p a rtic le so f
th e
p re s e n t in v e n tio n
is
a t
least partially
i n
th e
fo rm
o f
A g40
4-th a tis, silver II oxide. In a m oleculeo f this m aterial
1 5
tw oo f th e silv er ato m s a rei n th e1 + state (silv er I) w h ile th e
o th e r tw o
s ilv e r m o le c u le s a rei nth e
3 +
s ta te
(silver III).
U n d e r c e rta in c o n d itio n s th e s e m o le c u le s c a n g iv e ris e to
s ilv e r a to m si n th e Y
(silver II) state.
A further classo fe m b o d im e n ts is th e c o m b in a tio n o fa n y
2 0
o fth e a b o v e -d e s c rib e d e m b o d im e n ts w ith h y d ro g e n p e ro x \ue000
id e , a t a le v e lo f1 -3w gt%
h y d ro g e n p e ro x id e in th e fin a l
p ro d u c t.
P R E F E R R E D
E M B O D IM E N T S
N o n -lim itin g p re fe rre d e m b o d im e n ts a re p re s e n te d in th e
fo llo w in g :
A
c o m p o s itio n
c o m p ris in g
s ilv e r
p a rtic le s ,
c o llo id a lly
s u s p e n d e d

in w a te r, w h e re in th e to ta l c o n te n to fsilver is b e tw e e n 5 a n d 4 0 p p m , w h ic h c o m p o s itio n k illso rd is a b le s m ic ro o rg a n is m s w h ic h a re h a z a rd o u s to th e h u m a n b o d y .

A
c o m p o s itio n
c o m p ris in g
s ilv e r
p a rtic le s ,
c o llo id a lly
s u s p e n d e d
in w a te r, w h e re in th e to ta l c o n te n to fsilver is
2 5
a b o u t 1 0 \u00b1 2 p p m , w h ic h c o m p o s itio n k illso r d is a b le s m ic ro \ue000
organism s w hich are hazardous to the hum an body.
A
c o m p o s itio n
c o m p ris in g
s ilv e r
p a rtic le s ,
c o llo id a lly
s u s p e n d e d
in w a te r, w h e re in th e to ta l c o n te n to fsilver is
a b o u t 2 2 \u00b1 2 p p m , w h ic h c o m p o s itio n k illso rd is a b le s m ic ro -
3 0
organism s w hich are hazardous to the hum an body.
A
c o m p o s itio n
c o m p ris in g
s ilv e r
p a rtic le s ,
c o llo id a lly
s u s p e n d e d

in w a te r, w h e re in th e to ta l c o n te n to fsilver is a b o u t 3 2 \u00b1 3 p p m , w h ic h c o m p o s itio n k illso rd is a b le s m ic ro \ue000 organism s w hich are hazardous to the hum an body.

I tw ill b e a p p re c ia te d th a t s p e c ify in g th e to ta l a m o u n to f
s ilv e ri n
a
c o m p o s itio n
o fp a rtic le s
d o e s
n o t c o m p le te ly
s p e c ifY

the m aterial. As the particles com prising the com \ue000 p o s itio n a re m a d e sm a lle r, a g iv e n c o n c e n tra tio no fs ilv e r w ill re p re s e n t a la rg e r n u m b e ro fp a rtic le s .I n a d d itio n , th e

4 0
to ta l
s u r f a c e
a r e a
fo r
a
g iv e n
s ilv e r
c o n c e n tra tio n
w ill

increase. T herefore, particles size and rangeo fparticle size isa nim p o rta n t p a ra m e te r fo r d e fin in g a ne ffe c tiv e in v e n tiv e c o m p o s itio n .

A
fu rth e r
c la s s
o fe m b o d im e n ts
is
a n y
o fth e
a b o v e -
4 5
d e s c r ib e d
c o m p o s itio n s ,
w h e re in
m ore
th a n
5 0 %
o fth e
s ilv e r p a rtic le s h a v e a m a x im u m
d im e n s io n le s s th a n 0 .0 1 5
m icrom eters.
A
fu rth e r
c la s s
o fe m b o d im e n ts
is
a n y
o fth e
a b o v e \ue000
d e s c r ib e d
c o m p o s itio n s ,
w h e re in
m ore
th a n
7 5 %
o fth e
5 0
s ilv e r p a rtic le s h a v e a m a x im u m
d im e n s io n le s s th a n 0 .0 1 5
m icrom eters.
A
fu rth e r
c la s s
o fe m b o d im e n ts
is
a n y
o fth e
a b o v e \ue000
d e s c r ib e d
c o m p o s itio n s ,
w h e re in
m ore
th a n
9 0 %
o fth e
s ilv e r p a rtic le s h a v e a m a x im u m
d im e n s io n le s s th a n 0 .0 2
5 5
m icrom eters.
A
fu rth e r
c la s s
o fe m b o d im e n ts
is
a n y
o fth e
a b o v e \ue000
d e s c r ib e d
c o m p o s itio n s ,
w h e re in
m ore
th a n
7 5 %
o fth e
s ilv e r p a rtic le s
h a v e
a
m inim um
d im e n s io n
g re a te r th a n
0 .0 0 5 m ic ro m e te rs .
A
fu rth e r
c la s s
o fe m b o d im e n ts
is
a n y
o fth e
a b o v e \ue000
d e s c r ib e d
c o m p o s itio n s ,
w h e re in
m ore
th a n
9 0 %
o fth e
s ilv e r p a rtic le s
h a v e
a
m inim um
d im e n s io n
g re a te r th a n
0 .0 0 5 m ic ro m e te rs .
A
fu rth e r
c la s s
o fe m b o d im e n ts
is
a n y
o fth e
a b o v e -
6 5
d e s c r ib e d
c o m p o s itio n s , w h e re in th e
s ilv e r p a rtic le s c o m \ue000
prise b o th silver in th e

se ts fo rth th e b e s t m o d e s c o n te m p la te d b y th e in v e n to ro f c a rry in g o u t h is in v e n tio n . V a rio u s m o d ific a tio n s , h o w e v e r, w ill re m a in re a d ily a p p a re n t to th o s e s k ille di nth e art, sin ce th e

g e n e ra l p rin c ip le so fth e
p re s e n t in v e n tio n h a v e
b e e n

d e fin e d h e re in s p e c ific a lly to p ro v id ea nim p ro v e d c o llo id a l s ilv e r p ro d u c t w ith s ig n ific a n t a b ilitie s to k ill h u m a n p a th o \ue000 gens bothi nv iv o a n d i nv itro .

G e n e ra lly ,
th e
p r e s e n t
in v e n tio n
r e p r e s e n ts
a
n o v e l
a p p r o a c h to k illin go rd is a b lin g m ic ro o rg a n is m s w h ic h a re
h a z a rd o u s to h u m a n b e in g sb yth e u s eo f s ilv e r p a rtic le si n
1 0
w a te r, a t a c o n c e n tra tio no f 5 to 4 0 p p m
s ilv e r. D e p e n d in g
u p o n th e
a p p lic a tio n , th e

s ilv e r c o m p o s itio n m a yb eu s e d in te rn a lly o r e x te rn a lly . D e p e n d in g o n th e a p p lic a tio n , th e s ilv e r c o m p o s itio n m a y a ls o c o n ta in h y d ro g e n p e ro x id e .

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Colloidal silver is also effective against E. coli bacteria, as evidenced by the 7 different clinical studies discussed in this article: http://thesilveredge.com/cs_ecoli.shtml

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