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Tb Drugs Ripe

Tb Drugs Ripe

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Published by ronletaba

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Published by: ronletaba on Jun 23, 2009
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02/04/2013

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Name of DrugClassificationMechanism oactionIndicationcontraindicationSide EffectNursingResponsibilitiesGeneric Name:rifampicinBrand Name:CrisarfamAnti-infectivesInhibits DNA-dependentpolymerase,decreasesreplication.Maintenancephase treatmentof all forms of pulmonary andextra-pulmonaryTB; prevention of meningococcalmeningitis.Jaundiceassociated withreduced bilirubinexretion; 1
st
trimester of pregnancy;premature andnewborn infants.Drug-induced liver diseas, impairedliver function.GI disturbances,N/V, diarrhea andanorexia. SOB,shock. GIbleeding, erosivegastritis, ulcerativecolitis, Liver andkidneydysfunction,gastritis. -Performmycobacterialstudies andsusceptibility.Assess lungsounds andcharacter andamount of sputumperiodically.Monitor patientcompliance withtreatmentregimen.Do not take anymedication duringtherapy w/oconsultingphysician.Take rifampin onan emptystomach, 1 hour or after meals.This medicationwill discolor urine,stool, saliva, tears,sweat, and other body fluid a red-brown color.-Source: PPD’s Nursing Drug Guide, 2007 Edition, page 166
 
Name of DrugClassificationMechanism oactionIndicationContraindicationSide EffectNursingResponsibilitiesGeneric Name:isoniazidBrand Name:NorvitAnti-infectivesInhibits RNAsynthesis,decreasestubercle bacillireplication.Pulmonary andextrapulmonarytuberculosis (TB).Should not begiver\n to patientswith drug inducedliver diseas.Various skineruptions, fever,lymphadenopathy,and vasculitis,hypersensitivity,N/V, GIdisturbances, liver dysfunction.Assess laboratoryexaminations.Monitor liver/renalfunction.Instruct patientthat compliancewith dosageschedule for duration isnecessary to gainbenefits.Caution patient inalcohol while intherapy mayincrease risk of liver damage.Tell patient toreport peripheralneuritis.-Source: PPD’s Nursing Drug Guide, 2007 Edition, page 137.
 
Name of DrugClassificationMechanism oactionIndicationContraindicationSide EffectNursingResponsibilitiesGeneric Name:pyrazinamideBrand Name:MycobakAnti-infectivesMechanismunknown, highlyspecific andbactericidal for Mycobacteriumtuberculosishominis.Treatment of active tuberculosisin adults andselected childrenAcute-liver disease,porphyria,peripheral neuritis,acute gout,hypersensitivityand pregnancy.Dose-relatedhepatoxicity, N/V,anorexia,thrombocytopenia,increased serumiron concentrationand adverseeffects on bloodclottingmechanisms.Assess patientscondition beforetherapy andregularlythereafter tomonitor drugeffectiveness.Monitor serum uricacid which may beelevated andcause goutsymptoms.Regularly assessfor hepatoxicity.Regularly assessrenal status.Instruct patient totake drugcontinuously asprescribed.Remind patient tocomply withfollow-upschedule.Source: PPD’s Nursing Drug Guide, 2007 Edition, page 164.

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