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US-USSRAgreement.Af1emoranctllmof.Understandingforcooperationinthe'!
".!:'
ofthemicrobiology,irrrnunoloQY,andmolecularbiologyofcancerviruses.·'I~·firstsigned
on
November18,i~72.The11emorandumestablishedproceduresri~rjointstudiesthroughtheexchangeofinfonnation,.iTtaterialsandscienti;':betwecnthehiOcountries.
\
Delegatesexpressedinterestinconductingcollaborativestudiesinthe.followingareas:(1)studiesofvirusesisolatedfromhumantisslJesin,;cl!cultureorinanimalsandtheirpossibleroleinthepathogenesisofh,",.ll1neoplasia;(2)continuationofstudiesonnon-humanprimatevirusesas'
[ill'"
relatetohumancancer;(3)studiesontheroleofvirusesintheindu(~i"'lofhumanbreasttumors,inc1udingcontinuationofstudiesonI1PMVandrcl,)"d
viruses;
(4)studiesoncocarcinngenesisuvirul/vi:'al,virol/cl:e:::icill.or:.;viral/hormonal;(~)characterizationofnucleicacid~andtheirroleill1.1'"inductionofanimalandhumancancers,particula;-lythedetectionoftra'1s·formingsequencesin.cellularnucleicacidsandmoleculargeneticstudie·.withDNAfromhumantumorcells;(6)studiesonviralproteinsasprobocforviral
gene
expressioninanimalsandhun\1ns;and(7)studiesononC"':",!,;virusesimportanttohUf1lJnecology.e.g.,thosederivedfrombovine.a:,i'III,Asagreed,thefifthm~etingoftheUS-USSRJointflorkingGroupon
Cancer
Virology,Co-ChairmenOr.J.B.lIoloneyandProfessorV.ltZhdanov,tookplaceattheNationalInstitutesofHealth,·Bethesda,r·:aryland,USA,onOctober26-28,1977.AtasymposiumheldonOctober27and28.membersofbothdelegationsandinvitedspeakerspresentedrecentst~diesincancer
virology.
Themainemphasisofthismeetingwasgiventoreviewingtheprogress'ofcurrentcooperativeeffortsandassessingtheproblcmofrecombinantDNAresearch.Or.r~ichaelCrawford(UniversityofKansas)presentedpreliminary'resultsofastudytodeterminetheroleofgeneticfactorsinanoutbreakofleukemiainbaboons.This\lork,conductedjointJ~:bylaboratories
in
theUSAandintheUSSR.isanexcellentexampleofthecooperativeresearcheffortssponsoredundertheUS-USSRAgreement.TheChairmenofbothSidesreportedontherecorrrnendationsmadeintheMemorandumofUnderstandingoftheJointCorrmitteeonf1a1ignantNe~p
1015
i,iheldinHoscow,USSR,September,1977.TherecollJ11endationsincluded:(1)discussing,indepth.cooperativestudiesonrecombinantDNAresearch,2)increasingtheprogrampartiCipationofotherUSSRinstitutions,inparticulartoincludetheInstituteofliolecularBiology,lioscow,(3)C~n·ductingexchangesofscientistsonlyundertheauspicesoftheCancerVirologyProgramunderthetopicofMaIi9nantNeoplasia,USA-USSRHea1thAgreement,and(4)encouragingtheuse'ofsmallworkinggroupmeetiogs
1)11
subjects'ofintenseinterest...
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Title:C~ntorjal?~eserlation~nd:Jevel~!re'ntof
°ei2renc~·Grade
T:P'.orVirusesContractor'sPro;ec:~irec:ors:i;r.Charles~..~ldr;o
Pro;ect
~fficer'S
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Dr.
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ofse1ec:e1
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r
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:r~~eridls.Toserveasan3rc~iv~1r~'Jsitoryforsee-jSleeks
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md
Logisticshascontinued.Dat.!on
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Cire:tedDNApoly:::erase
offiverurfne!r.d~;Jrl"..ate
V'J"'I1SeS
h.J~
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de·~e\c::ed.Se!"!:b9k:a~'
ao.alysisof951u)dgsJ
anti;~nsugses~~s~'~ng
crossreac.t1'/1ty
t'-P.t·~€e"
squirrelronkeyr-etr:::yir~sand1'a5=n-Ffize~\l;)nkeyVir;s.The:entrac~'
reportsaTaCtafcorrelati-::11
bet,,~enio
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Delegationfleetings:.November,1972November,1973Nay,1974l1ay,1975
June.
1976
October,1977September,1978flosCOli,USSRBethesda,USA(Subcol1'mittce).r~oscow,USSRBethesda,USASukhumi,USSRBethesda,USARi9a•.latvianSSR
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