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Research group for Biomedical Instrumentation & Technologies, http://bmit.etf.rs/ University of Belgrade, Faculty of Electrical Engineering
Nikola Tesla
University of Belgrade, Faculty of Electrical Engineering Bulevar Kralja Aleksandra 73, Belgrade, Serbia Tel: +381/11/3218-348 Fax: +381/11/3248681
http://www.etf.bg.ac.rs/
The Laboratory follows strict ethical policy based on Helsinki declaration. The experimental work in the laboratory includes only healthy individuals. The validation of methods and instruments in individuals with health impairments take place by our clinical partners and collaborators with medical background and qualifications.
The main direction of activities is the development of clinical devices with the overall goal to design systems which could in the future replace the import of expensive electrophysiological and other equipment. Among other, we developed the system for acquisition and processing of data in nuclear medicine (gamma camera) that is used within the Clinical Center of Serbia, Belgrade and Clinical Center of Vojvodina, Novi Sad. We developed a polyEMG and EMNG systems that are used for research in the Institute for rehabilitation "Dr Miroslav Zotovi". We also developed research tools and devices that are used in clinical environment.
In relation to the strong research and scientific interest of the staff specific attention is dedicated to motor neural prostheses. In the Laboratory we are developing various elements needed for functional use of electrical stimulation and rehabilitation of movement (electrodes, controllers, stimulators, sensors systems, walking assists, etc.) that among other resulted in professional collaboration with private industry and patents.
The primary goal of the Lab is to provide logistic support for the development and design of new analog and digital interfaces for biomedical applications. The Laboratory is based on advanced computerized equipment that comprises National Instruments interfaces to body signals. The data acquisition software is based on LabVIEW (National Instruments, Austin, Texas, USA) and MatLab (The Mathworks, Natick, MA, USA).
PhD students:
Milica Jankovi Milica uri-Jovii Lana Popovi-Maneski Neboja Maleevi Ivana Milovanovi Nadica Miljkovi Andrej Savi Milo Kosti
BMIT activities
In last year, under TREMOR project, we started studying of the EEG signals and its use in BCI applications in BMIT laboratory. We incorporated our results in the course materials at the Faculty of Electrical Engineering, University of Belgrade, within Signals and systems in organisms, Acquisition Systems for Electrophysiology, Neural Engineering, and Methods for Processing Electrophysiological Signals (http://automatika.etf.bg.ac.rs). In course of Signals and systems in organisms students have practical demonstration of EEG acquisition and BCI algorithms. Through interactive classes and laboratory exercises in course of Acquisition Systems for Electrophysiology students learn how to design and use EEG acquisition systems. Students learn how to process EEG signals using advanced ICA (Independent Component Analysis) methods and time-frequency methods in the course of Acquisition Systems for Electrophysiology. In the master course of Neural Engineering we started working on series of student projects including acquisition, processing, and appliance of EEG signals in BCI applications. Results from these projects will be presented in the BAW on 16th March 2011. year at the Faculty of Electrical Engineering, University of Belgrade. We developed Matlab (The Mathworks, Natick, USA) software for offline processing and LabVIEW (National Instruments Inc, Austin, USA) online acquisition software that is constantly upgraded.
NI LabVIEW (ver. 8.6) program for EEG and EMG signal acquisition and on-line voluntary movement detection designed in BMIT laboratory under TREMOR project
During last year, our study covered large part of different techniques for BCI controls that are used in worlds largest research centers. Those techniques are MRP (Movement Related Potentials), ERD/ERS (Event Related Desynchronization/Synchronization), P300, and SSVEP (Steady State Visual Evoked Potentials). We have conference papers derived from BCI research in national and international conferences and certain number of diploma and master projects.
Accuracy of ERD detection for finger-to-nose movement designed in BMIT laboratory under TREMOR project. Eight plots of the left (red) and eight plots of right (black) arm movement of the 5th subject are shown for the frequency band: 8-11 Hz. X-axis is time where 0 is the onset of the movement. Y-axis is the ERD detection accuracy [0 - 100 %].
Our current activities are focused on exploring the latest applications of BCI in combination with assistive technology for the neurorehabilitation and for use in entertainment industry (for example: BCI control of computer games).
Part of the research done in BMIT laboratory will be presented in BCI demonstration and Brain competition during BAW. Our PhD students will show others how to place EEG electrodes, use acquisition systems, record signals, process them, and what are the problems in all those steps during demonstration. We decided to use Lego robot (National Instruments, Austin, USA) which velocity control is programmed in LabVIEW (National instruments, Austin, USA) and controlled by alpha waves of the subject for competition task during BAW. The BMIT laboratory and the Faculty of Electrical Engineering, University of Belgrade are certified to be an official LabVIEW school. BMIT laboratory is involved in TEMPUS project and BAW is also directed in the sense of biomedical science popularization among students.
Results obtained using pseudo-online movement detection algorithm on the data from Pat05, task: finger to nose, trial 1 and channel 7 recorded in BMIT laboratory as a part of TREMOR project
We have chosen one of EEG experiments performed in our laboratory, involving binaural beats impact on brain waves, to be present in this material.
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Figure 1, Spectrogram of EEG recordings from relaxed healthy subject during listening of music with binaural beats. The change from alpha to theta rhythm occurred at approximately 3.5 minutes after the onset of music with BBs.
Since theta activity is related to meditative states, we believe that this change in brain activity might be caused or partly induced by listening to binaural beats, [4]. Nevertheless, we suggest that this result needs to be confirmed in broader experiment. Results may have practical application in neurorehabilitation. References:
1. Schwarz DWF, Taylor P (2004) Human auditory steady state responses to binaural and monaural beats. Journal of Clinical Neurophysiology, 116(2005): 658-668. 2. http://www.youtube.com/watch?v=0wSUnuq7HPM 3. Sanei S, Chambers JA (2007) EEG signal processing. John Willey & Sons, Ltd, Cardiff University, UK. 4. Holmes Atwater F (2009) Binaural beats and the regulation of arousal levels. TMI Journal, 1(2009): 1-17.
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Organization Comittee: Andrej Savi, PhD student Nadica Miljkovi, PhD student
Organization: Matija trbac, master student Marko Markovi, master student Jovana Maleevi, graduate student Tijana Jevti, graduate student
Poster presenters: Andrej Savi, PhD student Una Kisi, PhD student Marko Filipovi, master student Nikola obaji, master student Jovana Beli, master student Marko Jevremovi, master project
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