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ACID-BASE IMBALANCE
 
byDr. Ali H. Sadiek
Prof. of Internal Veterinary Medicineand Clinical Laboratory Diagnosis
Faculty of Veterinary Medicine, Assiut University
E-mail:
Sadiek59@yahoo.com
 
 
Course Objectives
•What are the Acid-base and BloodGases?•How its measured?
•Causes, signs, and Lab. diagnosis of disorders in Acid-base imbalance:•Acidosis (Metabolic and Respiratory),•Alkalosis (Metabolic and Respiratory),
 
 
ACID-BASE BALANCE
Acid-base balance means that the net quantity of acid or base ingested or produced are quantitatively excreted by the lungs and kidney. In this case, the systemic pH will be stable and in balance and the bodybuffers preserved.Major physiologic acid/bases ingested or produced:
 
-HCO3-Lactate-B-OH butyrateCO2Lactic acidB-OH butyric acidOrganic-OH-NH3-SO4-HPO4+HHCLH2SO4H2PO4Mineral
Base gainAcid gain
The body produces more acids than bases
•
Acids produced by foods, metabolism of lipids and proteins + Cellular metabolism produces CO2.
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