Professional Documents
Culture Documents
lect/ST1/cardio
Circulation Reviewed
Blood Vessels "closed circulation"
Arteries from heart Capillaries cell exchange Veins to heart
Overview
lect/ST1/cardio
lect/ST1/cardio
lect/ST1/cardio
The Arteries
Arteries and arterioles take blood away from the heart. The largest artery is the aorta. The middle layer of an artery wall consists of smooth muscle that can constrict to regulate blood flow and blood pressure. Arterioles can constrict or dilate, changing blood pressure.
lect/ST1/cardio 9
The Veins
Venules drain blood from capillaries, then join to form veins that take blood to the heart. Veins have much less smooth muscle and connective tissue than arteries. Veins often have valves that prevent the backward flow of blood when closed. Veins carry about 70% of the bodys blood and act as a reservoir during hemorrhage.
lect/ST1/cardio 10
lect/ST1/cardio
11
The Capillaries
Capillaries have walls only one cell thick to allow exchange of gases and nutrients with tissue fluid. Capillary beds are present in all regions of the body but not all capillary beds are open at the same time. Contraction of a sphincter muscle closes off a bed and blood can flow through an arteriovenous shunt that bypasses the capillary bed.
lect/ST1/cardio
12
The Capillaries
lect/ST1/cardio
13
lect/ST1/cardio
14
Capillary exchange
lect/ST1/cardio
15
lect/ST1/cardio
16
The heart
The heart is a cone-shaped, muscular organ located between the lungs behind the sternum. The heart muscle forms the myocardium, with tightly interconnect cells of cardiac muscle tissue. The pericardium is the outer membranous sac with lubricating fluid.
lect/ST1/cardio 17
The heart has four chambers: two upper, thin-walled atria, and two lower, thick-walled ventricles. The septum is a wall dividing the right and left sides. The tricuspid valve on the right and the bicuspid valve on the left; both valves are reenforced by chordae tendinae attached to muscular projections within the ventricles.
lect/ST1/cardio 18
CARDIAC OUTPUT
volume of blood pumped by each ventricle CO = HR (heart rate) (x/mnt) x SV (stroke volume) (mL/beat)
Heart rate is the number of heart beats per
minute; normally it is about 70 beat/ minute Stroke volume is the volume of blood pumped by each ventricle per beat; normally it is about 70 ml/ beat
lect/ST1/cardio
20
Extrinsic control:
Sympathetic stimulation strength of contraction of cardiac muscle Mechanism : sympathetic stimulation release of norepinephrine increased permeability of muscle cell membranes to calcium calcium diffuses in more crossbridges are activated stronger contraction
lect/ST1/cardio 21
lect/ST1/cardio
22
The Heartbeat
Each heartbeat is called a cardiac cycle. When the heart beats, the two atria contract together, then the two ventricles contract; then the whole heart relaxes. Systole is the contraction of heart chambers; diastole is their relaxation. The heart sounds, lub-dup, are due to the closing of the atrioventricular valves, followed by the closing of the semilunar valves.
lect/ST1/cardio 23
lect/ST1/cardio
24
lect/ST1/cardio
25
lect/ST1/cardio
26
lect/ST1/cardio
27
The Electrocardiogram
An electrocardiogram (ECG) is a recording of the electrical changes that occur in the myocardium during a cardiac cycle. Atrial depolarization creates the P wave, ventricle depolarization creates the QRS wave, and repolarization of the ventricles produces the T wave.
lect/ST1/cardio
28
Electrocardiogram
lect/ST1/cardio
29
Blood Flow
The beating of the heart is necessary to homeostasis because it creates pressure that propels blood in arteries and the arterioles. Arterioles lead to the capillaries where nutrient and gas exchange with tissue fluid takes place.
lect/ST1/cardio
30
lect/ST1/cardio
32
lect/ST1/cardio
33
lect/ST1/cardio
35
Temperature
Cold vasoconstriction Heat vasodilation
lect/ST1/cardio
36
lect/ST1/cardio
37
lect/ST1/cardio
38
lect/ST1/cardio
39
BLOOD PRESSURE
lect/ST1/cardio
40
EDEMA
1. Reduced concentration of plasma proteins.
Factor that reduce plasma proteins include:
Kidney disease can result in the loss of plasma proteins in the urine. Liver disease can decrease the synthesis of plasma proteins. A protein-deficient diet will decrease plasma proteins. Severe burns result in a loss of plasma proteins (albumin) at the burn site
4. Blocked Lymphatics.
lect/ST1/cardio 42
Risk Factors
Non Modifiable
age male sex family history Race
Modifiable
physical inactivity cigarette smoking hypertension elevated serum cholesterol levels
4 known triggers
vigorous exercise or exertion exposure to cold or wind psychological or emotional stress eating a big meal
lect/ST1/cardio 43
Contributing Factors
obesity diabetes response to stress personality
Cardiovascular Disorders
Cardiovascular disease (CVD) is the leading cause of death in Western countries. Modern research efforts have improved diagnosis, treatment, and prevention. Major cardiovascular disorders include atherosclerosis, stroke, heart attack, aneurysm, and hypertension.
lect/ST1/cardio 44
Atherosclerosis
Atherosclerosis is due to a build-up of fatty material (plaque), mainly cholesterol, under the inner lining of arteries. The plaque can cause a thrombus (blood clot) to form. The thrombus can dislodge as an embolus and lead to thromboembolism.
lect/ST1/cardio
45
Partial blockage of a coronary artery causes angina pectoris, or chest pain. An aneurysm is a ballooning of a blood vessel, usually in the abdominal aorta or arteries leading to the brain. Death results if the aneurysm is in a large vessel and the vessel bursts. Atherosclerosis and hypertension weaken blood vessels over time, increasing the risk of aneurysm.
lect/ST1/cardio 47
lect/ST1/cardio
49
Angioplasty
lect/ST1/cardio
51
lect/ST1/cardio
52
Hypertension
About 20% of Americans suffer from hypertension (high blood pressure). Hypertension is present when systolic pressure is 140 or greater or diastolic pressure is 100 or greater; diastolic pressure is emphasized when medical treatment is considered. A genetic predisposition for hypertension occurs in those who have a gene that codes for angiotensinogen, a powerful vasoconstrictor.
lect/ST1/cardio 53
Variety of causes/ risk factors of hypertension are known - sedentary lifestyle - smoking - obesity - diet (excess sodium; cholesterol; calories in general) - stress - arteriosclerosis - genetic factors
lect/ST1/cardio
54
THANKYOU