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Published by ianecunar

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Published by: ianecunar on Jul 04, 2009
Copyright:Attribution Non-commercial


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Brand name:
AmoclavGeneric name:
Amoxicillin and Clavulanic acid
infections caused by susceptible beta-lactamase-producing organisms: lower respiratory tract infections, otitis media, sinusitis, skin and soft tissue infections,UTI, pre and post surgical procedures.
Drug classification:
antiinfective; beta-lactam antibiotic; amino penicillin
Mechanism of action:
used alone, clavulanic acid antibacterial activity is weak. Incombination, it inhibits enzyme (beta-lactamase) degradation of amoxicillin and bysynergism extends both spectrum of activity and bactericidal effect of amoxicillinagainst many strains of beta-lactamase-producing bacteria resistant to amoxicillinalone.
tab: Adult & children> 12 yr mild to moderate dental infection 375mg tid. Severeinfection 625mg tid or 1g bid. 312mg/5ml suspension. Children >6yr 5ml tid,156mg/5ml suspension. 1-6yr 5ml tid. <1yr 25mg/kg/d in divided doses every 8h inmore serious infections the dosage may be increase up to 50mg/kg/d in divideddosage every 8h. vial: Adult&children >12yr 1.2g 8h. severe infection 6h daily.3months-12yr 5/25mg/kg 8h, 0-3months 5/25mg/kg 12h. may increase to 8h.
Special precaution:
super infections involving pseudomonas or candida. Pregnancy andlactation.

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