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Pharmaceutical Engineering û II

Pharmaceutical Engineering û II

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Published by ngel nilu

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Published by: ngel nilu on Jul 06, 2009
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03/12/2013

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GUJARAT TECHNOLOGICAL UNIVERSITY
B. Pharm. Semester - 3
 
Subject Code 230002Subject Name Pharmaceutical Engineering IISr.No Course content1.
Content uniformity :
Importance of content uniformity, means of achieving content uniformity,Sampling techniques, statistical treatment, requirements of regulatoryagencies, (FDA, USP and European Pharmacopoeia)2.
Powder flow :
Importance of flow in pharmacy, Factors influencing powder/granules flow(moisture, particle size, etc.), Determination of angle of repose (AR) ,Hausner ratio (HR), Carr’s compressibility index (CI) , Sample calculations(examples), pharmacopoeial specifications for AR, HR and CI3.
Control charts and its applications in pharmacy
– elements of controlcharts and types of control charts, etc.,4.
Extrusion and Pelletization :
Factgors affecting pellet properties, Cold extrusion, Melt extrusion,Applications of extrusion in pharmacy (including preparation of solidsolution), selective equipments used for extrusion and pelletization, Use ofpolyethylene oxide and Eudragit in melt extrusion, Use of MCC inpelletization5.
Supercritical fluids :
Introduction to supercritical fluids, Pharmaceutical applications ofsupercritical fluids in extraction, size reduction, preparation of inclusioncomplexes, preparation of solid dispersions, etc., Equipments
Pharmaceutical Engineering – II – Practicals(
230002P)
 
Practicals related to topics in pharmaceutical engineering theory should be carriedout.Note: 1. Calculations shall be performed in EXCEL2. Graphs shall be drawn using EXCEL

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