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Published by thomjoanne

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Published by: thomjoanne on Jul 11, 2009
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02/04/2013

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Generic NameBrand NameClassificationDosage andRoute of AdministrationActionAdverseReactionContra-indication Nursing ConsiderationCefuroxime2
nd
generationcephalosporin.CeftinZinacef Anti-infections750 mg IV q8 hrs./ 15 g250 mg POq 12 hrs.Secondgenerationcephalosporin thatinhibitscell wallsynthesis, promotingosmoticinstability,usually bactericidad.CV: phlebitis,thrombolitisGI: pseudomembranouscolitis,nausea,anorexia,vomiting,diarrhea.HEMATOLOGIC:transient,neutrophenia,eosinophilia,hemolyticanemia,thrombocytopenia.SKIN:maculopapular anderythematousrashes,urticaria, pain,induration,sterileabscesses,temper Containdicatedin patienthypersensitiveto drugor other cephalos porins.Usecautiously in patienthypersensitiveto penicillin becauseof  possibility of cross-sensitivity withother  beta-lactamantibiotics.Usecautiously in breastfeedingwomenin patientwithhistoryof colitisObtain specimen for culture and sensitivitytest before giving 1
st
dose.For IM administrationinject deeply into alarge muscle mass,such as the gluteusmaximus or the lateralaspect of thigh.Absorption of cefuroxime axetil isenhanced by food.Cefuroxime axetiltablets may be crushedfor the patient cantswallow tablet.Alert: Cefuroximeaxetil film coate4dtablet and oralsuspension aren’t bioequivalent.If large doses aregiven,therapy is prolonged patient is athigh risk monitor for sign and symptoms andsuper infection.Alert: Don’t confuseddrug with other cephalosporin thatsound alike.
 
atureelevation,tissuesloughing at I.M.injectionsite.OTHER hypersensitivityreactions,serumsickness,anaphylaxis.andrenalinsufficiency.RanitidineZantacHistamineH2receptor  blockingdrug.50 mg IV q6-8 hrs.Competitivelyinhibitaction of histamineon the H2receptor sites of  parietalcells,decrease gastricacidsecretion.CNS:vertigo,malaise,headache.EENT: blurredvision,hepatic,jaundice.OTHER :burninganditchingatinjectionsite,anaphylaxis,angioedema.Contraindicatedin patientshypersensitiveto drugandthosewithacute porphyria.Usecautiously in patientswithhepaticdysfunction.Adjustdosagein patientswithimpairedrenalfunction.Assess patients for abdominal pain. Note presence of blood instool and emesis.Ranitidine may beadded to total parenteral nutritionsolutions.Alert: Don’t confuseranitidine withmantadine.Don’t confuse zantacwith xanax or zyrtec.
 
HyoscineHNBBCNSstimulant50 mgInhibitmuscarinic actionsof acetylcholine onautonomiceffectorsinnervated by postganglioniccholinergic neurons.May affectneural pathwaysoriginating in theinner ear to inhibitnauseaandvomiting.CNS:disorientation,restlessness,irritability,dizziness,drowsiness,headache,delirium,impairedmemory.CV: palpitation,tachycardia,paradoxical,bradycardia,flushing.EENT:dilated pupils,blurredvision,photopho bia,increaseintraocular  pressure,differentswallowing.GI:constipation,drymouth,nausea,vomiting,e pigastricdistress.GU:urinaryhesitancy,urineContaindicatedin patientwithangleclosureglaucoma,obstructiveneuropathy,obstr uctivediseaseof theGItract,asthma,chr onic pulmonarydisease,acutehemorrhage.Raise side rails as precaution becausesome patient becometemporarily excited or disoriented and somedevelop amnesia or  become drowsy.Tolerance may developwhen therapy is prolonged.Atropine like toxicitymay cause dose relatedadverse reactions.Alert: overdose maycause respiratory paralysis.

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