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HistologyHistologyof theof theReproductiveReproductiveSystemSystem
Ma. Minda Luz M. Manuguid, M.D.
 
 
EmbryologyEmbryology
Until the 6Until the 6
thth
week of fetal life, there isweek of fetal life, there isan indifferent primordial gonad with aan indifferent primordial gonad with acortex & a medullacortex & a medullaundifferentiated primordial genitalundifferentiated primordial genitalducts: the potential maleducts: the potential maleWolffianWolffianductsducts& the potential female& the potential femaleMullerianMullerianductsducts
 
 
EmbryologyEmbryology
Differentiation of the Gonads &Differentiation of the Gonads &Genital Ducts:Genital Ducts:-occurs from the 7-occurs from the 7
thth
to 8to 8
thth
weeks of weeks of fetal lifefetal lifeMale differentiation is due to theMale differentiation is due to thepresence of thepresence of theH-Y geneH-Y geneon theon the Y chromosome Y chromosomethatthatstimulates the primordial gonad tostimulates the primordial gonad todevelop into a testis (the medulla isdevelop into a testis (the medulla isstimulated, the cortex regresses),stimulated, the cortex regresses),which secreteswhich secretesTestosteroneTestosteroneFemale differentiation is the `default’Female differentiation is the `default’
of 00

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