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  • Terapi Hipotiroid

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    Fitrah Qolbina
    33 views7 pages
    TERAPI HIPOTIROID

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    TERAPI HIPOTIROID

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    TERAPI HIPOTIROID

    Copyright:

    Attribution Non-Commercial (BY-NC)
    Download as PPTX, PDF, TXT or read online from Scribd
    Flag for inappropriate content
    33 views7 pages

    Terapi Hipotiroid

    Uploaded by

    Fitrah Qolbina
    TERAPI HIPOTIROID

    Copyright:

    Attribution Non-Commercial (BY-NC)
    Download as PPTX, PDF, TXT or read online from Scribd
    Flag for inappropriate content
    of 7

    TERAPI HIPOTIROID

    Thyroid Hormone Replacement Therapy

    Synthetic levothyroxine (T4) Synthetic liothyronine (T3)

    Synthetic levothyroxine (T4)

    Farmakodinamik Dosis : Anak 10-15 mcg/kg/hari Dewasa 1.7 mcg/kg/hari 1x/hari Farmkokinetik Diminum 30menit-1jam sebelum makan Monitor setiap 2 bulan Puncak kerja 2 pekan Waktu paruh 3 pekan

    Synthetic liothyronin (T3)

    Dosis : 20mcg 3-4x/hari 3-4x lebih poten Farmakokinetik : puncak kerja 3 hari Lama kerja 1 pekan

    Kelebihan T4

    Stabil Murah Rendah reaksi alergi Monitor mudah Dosis sekali sehari

    Indikasi

    Pasien muda : full replacementherapy Koma miksedema : loading dose T4 300-400 mcg I/V initially 50 mcg daily Hypothyroidism and pregnancy : daily dose, adequate, monitored

    Kontraindikasi

    Pasien tua Pasien dengan penyakit jantung

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