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News for Mrsa

News for Mrsa

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Published by Kassa

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Published by: Kassa on Aug 09, 2009
Copyright:Attribution Non-commercial


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 Alternatives: Phage Therapy: Rediscovering a Treatment forSuperbug Infections
.At present, in addition to established organizations in Georgia, Russia and Poland that are reportedly marketing therapeuticand prophylactic phage products against bacteria including Staphylococci, Streptococci, E. coli, Pseudomonas, Proteus,Salmonella, Shigella, Serratia, Klebsiella, Enterobacter, Campylobacter, Yersinia and Brucella, there are an estimated 10companies located in the United States (Intralytix Inc: www.intralytix.com), Canada, India (GangaGen: www.gangagen.com)and Israel (Phage Biotech Ltd: www.phage-biotech.com) racing to provide a number of phage therapy products for a range ofmedical, animal husbandry, food processing and environmental applications. It is anticipated that the first phage-basedproducts for treatment of meat and poultry will receive FDA approval soon; an “experimental use permit” from EPA has beengranted for use of phages in the environment on non-food contact surfaces.
Info from The Epoch times link copied
Phage Therapy: Rediscovering aTreatment for Superbug Infections
By G. W. Riedel, PhDTheEpochTimes
May 31, 2005
Are North Americans allowed to suffer and die from antibiotic-resistant superbug infections unnecessarily? In the next two days44 Canadians and 110 Americans will die of antibiotic-resistant infections. The superbug deaths relentlessly advance causing40,000 U.S. and 8,000 Canadian deaths annually.While the mere mention of multiple antibiotic-resistant superbugs may strike doctors and patients with dread, they representthe opportunity to fulfill the raison d'être for the right bacteriophage. Superbugs’ presence excites the reproductive machineryof the phage into action. In stealth, moon-lander fashion, the phage commandeers the reproductive system of superbug. In ashort time (30 minutes) the superbug bursts open releasing more than 200 copies of phage, each looking for a superbug toconquer. While a superbug multiplies by dividing in two, the phage produces about 200 offspring for every superbug killed;clearly with those odds the superbug becomes the victim.Bactericidal, heat-labile, filterable principles in the Ganges and Jumna rivers in India were discovered in the 1890s, and it wassubsequently confirmed that many rivers with fecal pollution contained similar bactericidal agents. Tanner, in his 1944textbook, “Food Microbiology,” examines this phenomenon in some detail. It was d’Herelle, a French Canadian working inParis at the Pasteur Institute, who demonstrated in 1917 that the bacteria-lytic activity was due to viruses specific for bacteria—he named them bacteriophages—”bacteria eaters” and also advocated the use of phages for the treatment of bacterialinfections. Until 1940, phage therapy was widely practiced and researched, often with contradictory results, mainly becausethe biology of bacteriophages was poorly understood. With the introduction of antibiotics, phage therapy was essentiallyabandoned in the West until the 1980s when antibiotic-resistant superbug infections caused some Western scientists to re-
NEW PHAGE IN MEDICINE: A phage “moon landing” on asuperbug (antibiotic resistant microbe) into which it injectsphage proteins which become more phages to eliminatesuperbugs which cause infections and disease.Dr. Elizabeth Kutter 

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