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The SULPYCO Method: An Observational Study on the Efficacy of Low-dose Sulpiride Combined With a Complex Homeopathic Preparation for the Treatment of Depressive Syndrome

The SULPYCO Method: An Observational Study on the Efficacy of Low-dose Sulpiride Combined With a Complex Homeopathic Preparation for the Treatment of Depressive Syndrome

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Combined With a Complex Homeopathic Preparation for the Treatment of Depressive Syndrome
Context: Sulpiride is a commonly used treatment for depression in Europe and Japan. This is a study on the use of low-dose sulpiride in combination with a complex homeopathic preparation based on the Krebs-cycle elements for the treatment of depression.
Design: The author designed a relatively small, nonrandomized, observational study.
Setting: A private neurology clinic.
Participants: The participants were 67 women aged 28-55 y, with depressive symptoms diagnosed by a psychiatrist, who were seeking alternative forms of therapy. They reported that they had received no benefit from conventional antidepressant treatments.
Intervention: The treatments for the 3 groups were as follows: (1) the S/H group received a low dose of sulpiride (20 mg) and a homeopathic remedy (n = 25), (2) the S group received sulpiride only (n = 27), and (3) the H group received the homeopathic remedy only (n = 15). Participants received the treatments parenterally as once-daily subcutaneous injections for 3 mo.
Outcome Measures: Depressive symptoms were assessed semiquantitatively before and after treatment using the Hamilton rating scale for depression (HAMD).
Results: The HAMD score significantly decreased in the group treated with the combination of sulpiride and homeopathy, from 21.3 ?} 5.0 standard deviation (SD) before treatment to 8.8 ?} 4.1 SD after treatment (P Conclusion: This study suggests that a low parenteral dose (20 mg) of sulpiride, administered subcutaneously with a complex homeopathic remedy, may have a synergistic effect when used for treatment of mild to moderate depression. Further clinical testing in randomized, controlled trials is warranted.
Combined With a Complex Homeopathic Preparation for the Treatment of Depressive Syndrome
Context: Sulpiride is a commonly used treatment for depression in Europe and Japan. This is a study on the use of low-dose sulpiride in combination with a complex homeopathic preparation based on the Krebs-cycle elements for the treatment of depression.
Design: The author designed a relatively small, nonrandomized, observational study.
Setting: A private neurology clinic.
Participants: The participants were 67 women aged 28-55 y, with depressive symptoms diagnosed by a psychiatrist, who were seeking alternative forms of therapy. They reported that they had received no benefit from conventional antidepressant treatments.
Intervention: The treatments for the 3 groups were as follows: (1) the S/H group received a low dose of sulpiride (20 mg) and a homeopathic remedy (n = 25), (2) the S group received sulpiride only (n = 27), and (3) the H group received the homeopathic remedy only (n = 15). Participants received the treatments parenterally as once-daily subcutaneous injections for 3 mo.
Outcome Measures: Depressive symptoms were assessed semiquantitatively before and after treatment using the Hamilton rating scale for depression (HAMD).
Results: The HAMD score significantly decreased in the group treated with the combination of sulpiride and homeopathy, from 21.3 ?} 5.0 standard deviation (SD) before treatment to 8.8 ?} 4.1 SD after treatment (P Conclusion: This study suggests that a low parenteral dose (20 mg) of sulpiride, administered subcutaneously with a complex homeopathic remedy, may have a synergistic effect when used for treatment of mild to moderate depression. Further clinical testing in randomized, controlled trials is warranted.

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Published by: InnoVision Health Media on Nov 20, 2013
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12/24/2013

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