Welcome to Scribd, the world's digital library. Read, publish, and share books and documents. See more
Download
Standard view
Full view
of .
Save to My Library
Look up keyword
Like this
0Activity
0 of .
Results for:
No results containing your search query
P. 1
Drug Distribution

Drug Distribution

Ratings: (0)|Views: 4 |Likes:
Published by Rinta Moon
Volume of Distribution
Redistribution
Differences In Drug Distribution Among Various Tissues Arises Due To a Number of Factors
Tissue Permeability of the Drugs depend upon
Physiochemical Properties
PENETRATION OF DRUGS THROUGH BLOOD BRAIN BARRIER
PENETRATION OF DRUGS THROUGH PLACENTAL BARRIER
Blood – Cerebrospinal Fluid Barrier
Blood – Testis Barrier
Factor affecting drug-Protein binding , Significant , Kinetics of drug-protein binding
Binding of drug to blood cells
Tissue binding of drug
Factor affecting drug protein binding
Drug related factor
CONCENTRATION OF DRUG IN THE BODY
DRUG PROTEIN / TISSUE AFFINITY
Drug interaction
Volume of Distribution
Redistribution
Differences In Drug Distribution Among Various Tissues Arises Due To a Number of Factors
Tissue Permeability of the Drugs depend upon
Physiochemical Properties
PENETRATION OF DRUGS THROUGH BLOOD BRAIN BARRIER
PENETRATION OF DRUGS THROUGH PLACENTAL BARRIER
Blood – Cerebrospinal Fluid Barrier
Blood – Testis Barrier
Factor affecting drug-Protein binding , Significant , Kinetics of drug-protein binding
Binding of drug to blood cells
Tissue binding of drug
Factor affecting drug protein binding
Drug related factor
CONCENTRATION OF DRUG IN THE BODY
DRUG PROTEIN / TISSUE AFFINITY
Drug interaction

More info:

Published by: Rinta Moon on Dec 08, 2013
Copyright:Attribution Non-commercial

Availability:

Read on Scribd mobile: iPhone, iPad and Android.
download as PPT, PDF, TXT or read online from Scribd
See more
See less

12/08/2013

pdf

text

original

 
DRUG DISTRI UTION
02-12-2010 1 KLECOP, Nipani
 
 ontents
 Factors affecting on drug distribution
 Volume of distribution
 Factors affecting on protein Binding
 Kinetics of protein binding
 Significance of protein binding
 Reference
02-12-2010 2 KLECOP, Nipani
 
Introduction
Once a drug has gained excess to the blood stream, the drug is subjected to a number of processes called as Disposition Processes that tend to lower the plasma concentration. 1.Distribution which involves reversible transfer of a drug between compartments. 2.Elimination which involves irreversible loss of drug from the body. It comprises of biotransformation and excretion.
02-12-2010 3 KLECOP, Nipani

You're Reading a Free Preview

Download
/*********** DO NOT ALTER ANYTHING BELOW THIS LINE ! ************/ var s_code=s.t();if(s_code)document.write(s_code)//-->