β
-Blockers and Cardiac Events inNoncardiac SurgeryLessons from DECREASE-IV
M Chadi Alraies, MD
Department of Hospital Medicine Grand RoundCleveland Clinic Foundation
1M C Alraies
Agenda
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Perioperative cardiac events
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RCRI
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ACC/AHA Guidelines for perioperative BB use.
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What is already known about perioperative
β
-blockers
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Literature review
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DECREASE-IV study
2M C Alraies
Introduction
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About 20 million Americans undergo surgerywith general anesthesia each year.
1
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Cardiac events (MI or Cardiac death) result inperioperative mortality rate of 3-6%
1. July 20, 2005 Los Angeles Times
3M C Alraies
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MaVS trial 2006 for β-Blockers and Cardiac Events in Noncardiac Surgery
Beta blockers are known for their cardioprotective properties when used in noncardiac surgeries. This was one of the main principles in the perioperative medicine. However, lately this concepts being questions and this cardio protective properties have…
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