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Hemolytic Disease of Newborn

Hemolytic Disease of Newborn

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Published by cyphochilus

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Published by: cyphochilus on Sep 05, 2009
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02/07/2013

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HAEMOLYTIC DISEASE OF THE NEWBORNA 30 year old female had an abortionat 25 weeks.Foetus on exam wasseverly anaemic,had pleural effusionsand ascites(hydrop foetalis).The firstbaby is alive and well but onquestioning the mother indicated thatthe child was very “yellow” at birth.Her blood group is O negative.Husband’s is A positive. For someunknown reason anti-D injection wasnot given during the first pregnancyor immediately after delivery.QUESTIONS(a)Discuss the pathology of haemolytic disease of the new bornand complications in your patient.(b)Causes of hydrops foetalis( c)Other causes of haemolytic
 
INTRODUCTIONINTRODUCTION
Also known as erythroblastosisfoetalis
Haematological disease in thenewborn that occurs mostly due torhesus incompatibility
Mother is rhesus negative whilefetus is rhesus positive
Can occur due to non-immunecauses e. trisom 13
 
Rarely occurs in first pregnancyDisease is now reducing inincidenceRhoGAM vaccination

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