.

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.
2


, X D
D=FX, F
,:
Feret diameter
scan -
Martin diameter

 - Sieve Opening
- Hewood diameter

Stokes Diameter

Volume Diameter

Separation Methods Sieving, Impaction,

Electrostatic Differential Measurements
Field Scanning Methods Laser Diffraction,
Acoustic Attenuation
Sedimentation Method
Surface Method Permeability, Adsorption
Visual Methods Optical, Scanning Electron
Microscopy (SEM), Image Analysis

Visual Methods

Microscopy

SEM
,
Image Analysis
6

Separation Methods

- Sieving
.
.

Field Scanning Methods

- Laser Diffraction
()
. .
3000 0.1
.
- Acoustic Attenuation
.

Sedimentation Method

.
.
10 1
.

Surface Method

Adsorption
.

10

Blending and blend uniformity

-
()

11


.1
.2 ()convection
.3

12

 .1

-
.
-
,TUMBLER
,
.

13

 .2 ()convection

Convection
.
- RIBBON
- TUMBLER

14

 .3

,

( ).

HIGH SHEAR MIXERS
INTENSIFIERS -

15


.1

COHESIVITY

.2
.3
.4
.5

16

Cohesivity .1

( : ,
, , ) ,
.
-

17

 .2

.

.
,.

18

 .3

- .
( ) ,
.

19

 .4
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TRIBOELECTRIFICATION



( ,)AEROSIL ,
.
20

 .5

65-75% - - 40% -

21

 ()
-

22

 . ()

.1
.2
.3
.4

: 1 -.4-
23

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.1
.2
.3
.4

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.5
24

 . ()

.1 / ()sifting segregation
.2 ()fluidisation segregation
.3 ))dusting segregation

25

.1

/ ( )sifting segregation
:
.
:
1.3/1 100 - .

26

27

28

 .3

DUSTING SEGREGATION

50
.
.
.

29

 .2

100 , .
FLUIDISATION SEGREGATION

30


.1
.2
.3
.4
.5

/
,
,
,
,

31




.

:
32

()diffusion
((convection
()shear

33

,
. :
(- )fluidization ))FBD ()Tumblers

34

 ()convection

. :
()tumbler ()Ribbon - )(FBD

35

.
:
Intensifiers ()pin blenders36


Tumbler Blenders:
V- Blenders
Bin Blenders
Double cone Blenders
Slant cone Blenders

.1
: + -

High Shear Blenders:

: + -
Horizontal High Intensive Mixer )Lodige(
Vertical High Intensive Mixer (Diosna)
Screw/paddle Blenders:
Ribbon Blender
Planetary Blender
37

Fluid bed Blenders

: -

38

Bin Blender
39

40

41

 .2
. Tumbler
.
Ribbon Blender, Planetary Blender
High Shear Mixers
. FBD

42

43

High Shear Blender

Vertical High Intensive Mixer
Bottom driven(Diosna)

44

High Shear Blender

Vertical top driven

45

46

High Shear Blender

47

Horizontal High Intensity Mixer)Lodige(

48

Y-Cone -

Y-Cone -
49

50


.:
( )dosage form , ,
:
,Hiera Picra )MgSO4(Seidlitz Powder ,Sena
Dr. James Antimonial Powder 51

Bulk Powders
- Oral Powders
- Dentifrices
- Douch Powders
- Dusting Powders
- Insufflations
- Triturations

53

Oral Powders
()Effervescent Granules
, ,
NaHCO3 , .Na2HPO4 ,CO2
, .

54

Dentifrices
Abrasive -
Anticariogenic Agent -

55

Dusting Powder
Lubricants, Astringents, Antiperspirants -

Insufflation
, ,
Powder Blower

57

58

Triturations
,
( )1:10

59