•Nausea, vomiting, diarrhea.•
Hemolytic anemia (in patients deficient in G6PD)
Pulmonary hypersensitivity reactions
Subacutereactions-acute respiratory distress syndrome
( pulmonaryinfiltration, effusion-fever and eosinophiliamay occur-resolution may occur. –
more than 6 months therapy-chronic desquamative
interstitialpneumonitiswith fibrosis (resolution does not occur).
fatal.•Neurological disorders -headache, vertigo, drowsiness, muscular aches andnystagmus,
-Pregnant women at term, nursing mothers.-Infants less than 1 month and nursing infants-cellular damage and anemia.-Impaired renal function (creatinineclearance <40 ml/min).