Osteogenesis imperfecta (OI)
, also knownas Brittle Bone Disease, "Lobstein syndrome”or Fragilitas ossium.
People with OI are born with defectiveconnective tissue, or without the ability tomake it, usually because of a deficiency of Type-I collagen.
Occurs in 1:20,000 to 1:60,000 live births. OIcan affect males and females of all races.