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In-situ Ophthalmic Gel Ppt

In-situ Ophthalmic Gel Ppt

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Published by kscri
Eye is the unique organ of sight. conventionally various dosage forms are used but due to meagre bioavailability and residence time pharma researchers are trying for newer ocular dosage forms like in-situ gel, ocular films, ocuserts, liposomes, niosomes, dendrimers, collagen shields, SODI,biodegradable eye wafers and cones,iontophoresis etc. in this presentation more emphasis is given on in-situ gel forming techniques from various methods like pH, temperature and change in electrolyte composition. various polymers used for this purpose and very interesting rule of seven in eye also mentioned.
Eye is the unique organ of sight. conventionally various dosage forms are used but due to meagre bioavailability and residence time pharma researchers are trying for newer ocular dosage forms like in-situ gel, ocular films, ocuserts, liposomes, niosomes, dendrimers, collagen shields, SODI,biodegradable eye wafers and cones,iontophoresis etc. in this presentation more emphasis is given on in-situ gel forming techniques from various methods like pH, temperature and change in electrolyte composition. various polymers used for this purpose and very interesting rule of seven in eye also mentioned.

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Published by: kscri on Oct 02, 2009
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11/08/2012

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1Kamal Singh Rathore*, 2Nema R.K.,*1BN Girls College of Pharmacy, Udaipur-Raj.3130022Rishiraj College of Pharmacy, Indore-M.P.kamalsrathore@gmail.com+919828325713(M)
 
Eye anatomy
Rule of seven in eye anatomy:
Weight of both spheres:≈7.0 gm
Volume of eye: ≈7.0 mL
Circumference of eye: ≈ 7.0 cm
 Total protein in eye: ≈0.7% w/v
 Total sugar present: ≈0.7% w/v
 Total NaCl present: ≈ 0.7% w/v
 Total mineral elements(Na+, K+.NH3+): ≈0.7% w/v
Volume of lachrymal fluid : ≈7.0 μl
Corneal surface epithelialintracellular pore size: ≈0.7nm
Protein in blood: ≈7.0% w/vand
pH of lachrymal fluid (tears): ≈ 7.0
 
Conventional dosageforms
 The conventional ocular dosage forms for thedelivery of drugs are
Eye drops
Eye ointments
Eye lotion

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Kanchan Maske added this note
very nice ppt sir,
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sir, like this presentation
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very gud presentation
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nice presentation
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