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Pulmonary Embolism

Pulmonary Embolism

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Published by: ganga2424 on Oct 15, 2009
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05/19/2012

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 PULMONARY EMBOLISM
 B.GANGADHAR
 
PULMONARY EMBOLISM
Pulmonary embolism (PE) refers to exogenous orendogenous material that travels to the lungs throughthe pulmonary circulation, causing a potential spectrumof consequences.
 Thrombus from the deep veins of the lower extremities isby far the most common material to embolize to thelungs
 Tumor cells, air bubbles, carbon dioxide, intravenouscatheters, fat droplets, and talc in intravenous drugabusers are also potential sources of emboli.
 
PULMONARY EMBOLISM
Genetic and acquired factors contribute to the likelihood of VTE.
 The two most common autosomal dominant geneticmutations are the factor V Leiden and the prothrombingene mutations
However, only a minority of patients with VTE haveidentifiable predisposing genetic factors. The majority of patients with predisposing genetic factors will notdevelop clinical evidence of clotting

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