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Brand Name: Aprovel Generic Name: Irbesartan Indications: For the Treatment

Brand Name: Aprovel Generic Name: Irbesartan Indications: For the Treatment

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Published by ianecunar

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Published by: ianecunar on Oct 17, 2009
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04/04/2013

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Brand Name
:
AprovelGeneric Name
:
 
Irbesartan
Indications
: For the treatment of hypertension & treatment of renal disease in patients withhypertension and type II diabetes mellitus, as part of an antihypertensive drugregimen.
Drug Classification
: Antihypertensive
Mechanism of Action
:
 
Inhibits the vasoconstricting and aldosterone-secreting effects of angiotensin II by selectively blocking binding of angiotensin Ii to receptor sites in many tissues.Therapeutic Effect: Lowers blood pressure.
Dosage
: 150 mg daily. May be increased to 300 mg or combined with other antihypertensiveagents if patient is not sufficiently controlled. In hemodialyzed patients &elderly>75 yr 75 mg daily
Special Precaution
: Intravascular volume depletion, renovascular hypertension, renalimpairment, kidney transplantation, hyperkalemia, aortic & mitral valve stenosis,obstructive hypertrophic, cardiomyopathy, ischemic cardiopathy, ischemicCV disease, primary aldosteronism & patients whose vascular tone & renal functiondepend predominantly on the activity of the rennin-angiotensin-aldosterone system.
Pregnancy Risk Category
:
 
C (D in 2
nd
and 3
rd
trimesters)

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