Brand name: BlopressGeneric name
Management of hypertension, treatment of type 2 diabetic nephropathy in patients with type 2 diabetes, management of CHF in patients who cannottolerate ACE inhibitors.
: angiotensin II receptor antagonist
Mechanism of action:
Blocks vasoconstrictor and aldosterone producing effects of angiotensin II at receptor sites, including vascular smooth muscle and theadrenal glands. Therapeutic effects: Lowering of blood pressure, slowed progression of diabetic nephropathy, decrease risk of stroke.
: PO (adults): As monotherapy- 16mg once daily. Patients receiving diuretics or who are volume depleted- initiate therapy at a lower dose ( range 2-32 mg/dayas a single dose or divided into 2 daily doses)
Do not administer to patients with CHF ( may resilt in azotemia,oliguria or acite renal failure) and to patiemts who are salt depleted or patientsreceiving high doses of diuretics ( risk for hypotension)
Pregnancy risk category: C
(first trimester), D (second and third trimester)