Brand Name: CarnicorGeneric Name:
L-carnitine
Indications:
Chronic myocardia ischemia, cardiac failure, angina pectoris, arrhytmia,acute myocardial ischemia.
Drug Classification:
Cardiac Drugs
Mechanism of Action:
Facilitates the transport of fatty acids into cellular mitochondria.The fatty acids are then used to produce energy.
Dosage:
Chronic myocardia ischemia, cardiac failure Tab 2-3 tab tid. Inj 1 g bid-tid IV(slowly over 2-3 min) or IM. Angina pectoris, arrhytmia tab 2 tab tid. Inj 1 g bidIV (slowly over 2-3 min) or IM, acute myocardial ischemia.2 g bid-tid IV(slowly over 2-3 min) or IM. Soln 50-100mg/kg body wt.
Special Precaution:
Standard assays for mutagenicity indicate that L-carnitine is not mutagenic.Reproductive studies have been performed in rats and rabbits at doses up to 3.8times the human doses used for the treatment of primary and secondary L-carnitine deficiency on the basis of surface area and have revealed no evidenceof impaired fertility or harm to the fetus due to L-carnitine. However, there areno adequate and well-controlled studies in pregnant women. Because animal
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