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Critical Care Nursing
lecture notes in Critical Care class
Brand Name: DeciloneGeneric name
: Dexamethasone
Indications:
rheumatoid arthritis, systemic lupus, acute gouty arthritis, psoriatic arthritis,ulcerative colitis, and Crohn's disease. Severe allergic conditions: bronchialasthma, allergic rhinitis, drug-induced dermatitis, and contact and atopicdermatitis. Chronic skin conditions: dermatitis herpetiformis, pemphigus,severe psoriasis and severe seborrheic dermatitis. Chronic allergic andinflammatory conditions of the uvea, iris, conjunctiva and optic nerves of theeyes Blood cell cancers (leukemias), and lymph gland cancers (lymphomas).Blood diseases: idiopathic thrombocytopenia purpura ; autoimmune hemolyticanemia.
Drug Classification:
Synthetic adrenal corticosteroid; glucocorticoid type.
Mechanism of Action:
Corticosteroids are natural substances produced by the adrenalglands located adjacent to the kidneys. Corticosteroids have potent anti-inflammatory properties by preventing phospholipid release, decreasingeosinophil action and a number of other mechanisms. Dexamethasone, acorticosteroid, is similar to a natural hormone produced by your adrenal glands.
It often used to replace this chemical when your body does not make enough of it.
Dosage
PO: initial, 0.75-9 mg/day; maintenance, gradually reduce to minimum effectivedose (0.5-3 mg/day)
Special precaution:
Tell your doctor and pharmacist if you are allergic todexamethasone, if you're taking in anti- coagulants, and if you are pregnant.
Pregnancy risk:
Dexamethasone can be used in pregnancy, but is generally avoided.
Adverse reaction:
stomach irritation,vomiting,headache,dizziness, insomnia,restlessness, depression anxiety, acne, increased hair growth, easy bruising,irregular or absent menstrual periods, skin rash swollen face, lower legs, or ankles vision problems, cold or infection that lasts a long time, muscleweakness, black or tarry stool.
Contraindications
: Infection, peptic ulcer, acute glumerulonephritis
Form:
Tablet
Nursing Responsibility:
Assess patients on long term therapy have blood tests to determine glucoselevels an electrolyte balance
Assess patients muscles for weakness and wasting
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Brand Name: Decilone Generic Name: Dexamethasone Indications: Rheumatoid Arthritis, Systemic
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| Upload Date: | 10/17/2009 |
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