Acyclovir (Zovirax)
Cap: 200 mgInj: 500 mg, 1 gmOint: 5% [3, 15 gm]Susp: 200 mg/5 mLTab: 400, 800 mg
Herpes zoster (immunocompromised):
500mg/m2/dose PO 4-5 timesdaily or 1500 mg/m2/day IVq8h
Herpes zoster (immunocompetent):
80mg/kg/day PO 5 times daily(max 4000 mg/day) or 30mg/kg/day IV q8h
Varicella zoster (chickenpox):
80 mg/kg/day PO qid x 5days (max 3200 mg/day)
Mucocutaneous HSVinfection:
750 mg/m2/day IVq8h or 15 mg/kg/day IV q8h x7 days.
Genital herpes or HSV(immunocompromised):
80mg/kg/day PO 3-5 times daily(max 1000 mg/day)
Herpes encephalitis:
birth-12 yrs: 60 mg/kg/day IVq8h>12 yrs: 30 mg/kg/day IV q8hInfuse each IV dose over 1hour. Adjust in renalimpairment. Patients should bewell hydrated to avoidurolithiasis.
Topical:
Apply to affectedarea q3h while awake for 7days. avoid
Albendazole
Tab: 200 mg
Neurocysticercosis:
Patientshould also receiveappropriate corticosteroid andanticonvulsanttherapy if indicated.<60 kg: 15 mg/kg/day PO bidfor 8-30 days, max 800 mg/day>60 kg: 400 m PO bid for 8-30days
Roundworm, hookworm,whipworm:
Children and adults: 400 mgPO x 1For long-term therapy, monitor CBC and LFTs q2 weeks.
Albumin, human(Albuminar, Albumisol);Plasma Volume Expander
Inj: 5% [50, 250, 500, 1000mL], 25% [20, 50, 100 mL
Hypoproteinemia:
0.5-1gm/kg/dose IV infused over 2-4h; may repeat q1-2 days;(25% concentration preferred,consider giving furosemideafterwards)
Hypovolemia:
0.5-1gm/kg/dose IV infused over
10-60 minutes (5%concentration preferred, doseequals 10-20 mL/kg)Contains sodium 130-160 mEqper liter.
Albuterol (Proventil,Ventolin, Volmax, Rotacaps
)
MDI: 90 mcg/puff, 200puffs/canister [17 gm]Soln for nebulization: 0.5%(5 mg/mL) [20 mL]; 0.083%[3mL unit dose]Soln for nebulization(AccuNeb): 0.63 mg/3 mL;1.25 mg/3 mLSyr: 2 mg/5 mLTab: 2, 4 mgTab ER: 4, 8 mg;
Inhalation:
1-2 puffs q4-6hprn; spacers arerecommended for youngchildren.
Oral:
2-6 yrs: 0.1-0.2mg/kg/dose tid (max 4 mg/day)6-12 yrs: 2 mg/dose tid-qid or 4 mg ER bid>12 yrs: 2-4 mg/dose tid-qid or 4-8 mg ER bid
Nebulizer:
0.01-0.05 cc/kg of 0.5% soln (min 0.1 cc, max 1cc) in 2 cc NS or 0.15 - 0.25mg/kg of 0.083% soln (0. 83mg/mL, max 5 mg) q4-6h prn.AccuNeb: <12 yrs 0.63 - 1.25mg neb q4-6h prn, >12 yrs1.25 mg neb q 4-6h prn.Hospitalized patients mayrequire more frequent dosingwith higher concentrations of albuterol.Tachycardia, hypokalemia,CNS stimulation
.
Amikacin sulfate
Inj: 50 mg/mL [2 mL], 250mg/mL [2, 4 mL]
<5 yr (except neonates):
22.5mg/kg/day IV/IMq8h
5-10 yrs:
18 mg/kg/day IV/IMq8h
>10 yrs:
15 mg/kg/day IV/IMq8hInfuse over 30 minutes.Therapeutic peak levels 20-30mcg/mL and trough levels <8mcg/mL. Adjust dose in renalimpairment. Side effectsincludenephrotoxicity and ototoxicity.
Aminophylline
Inj: 25 mg/mLLiq: 105 mg/5 mLTab: 100, 200 mgTab CR: 225 mg;
IV Loading dose:
5-6 mg/kgIV over 20-30 minutes
Maintenance IV infusion:
1-6mos: 0.5 mg/kg/hr 6-12 mos: 0.6-0.75 mg/kg/hr 12 mos-10 yrs: 1.0 mg/kg/hr 10-16 yrs: 0.75-0.9 mg/kg/hr >16 yrs: 0.7 mg/kg/hr
Oral dose:
1-9 yrs: 16-19.2 mg/kg/day q6-12h9-12 yrs: 12.8 mg/kg/day q6-12h
12-16 yrs: 10.4 mg/kg/day q6-12h>16 yrs: 8 mg/kg/day q6-12hLiq or tab: q6-8h; CR tab: q8-12h
Therapeutic Levels:
10-20mcg/mL.Aminophylline contains 80%theophylline.Monitor serum levels andadjust dose as appropriate
Amoxicillin
Cap: 250, 500 mgDrops: 50 mg/mLSusp: 125 mg/5 mL, 250mg/5 mL, 400 mg/5 mLTab: 500, 875 mgTab, chew: 125, 200, 250,400 mg
25-50 mg/kg/day PO bid-tid(max 500 mg/dose); doses ashigh as 80-90 mg/kg/day PObid have been used to treathighly resistant strains of Streppneumoniae
Ampicillin
Cap: 250, 500 mgInj: 125, 250, 500, 1000,2000 mgSusp per 5 mL: 125, 250mg;
Sepsis:
100-200 mg/kg/dayIV/IM q4-6h (max 12 gm/day)
Meningitis:
200-400mg/kg/day IV/IM q4-6h (max12 gm/day)
Oral:
50-100 mg/kg/day POqid (max 2-3 gm/day)
Aspirin
Caplet, buffered: 325 mgSupp: 120, 200, 300, 600 mgTab: 325, 500 mgTab buffered: 325, 500 mgTab chew: 81 mgTab CR: 800 mgTab DR: 81 mgTab EC: 81, 165, 325, 500,650, 975 mgTab ER: 650 mg;
Kawasaki's Disease:
80-100mg/kg/day PO/PR q6h; oncefever resolves, decrease doseto 3-5 mg/kg/day PO qd.
Analgesic and antipyretic:
10-15 mg/kg/dose PO/PR q4-6h prn (max 4 gm/day)
Anti-inflammatory:
60-90mg/kg/day PO/PR q6h (max 4gm/day).Contraindicated in childrenwith fever because of risk of Reye's Syndrome. May causeGI bleeding and tinnitus. Takewith food.
Azithromycin
Packet, oral: 1 gmSusp per 5 mL: 100, 200 mgTab: 250, 500. 600 mg
Otitis Media: 5-day course
>6 months: 10 mg/kg (max500 mg) PO on day 1 followedby 5 mg/kg (max 250 mg) ondays 2-5
Otitis Media: 3-day course
>6 mos: 10 mg/kg PO qd x 3days, max 500 mg/day
Otitis Media: Single-DoseRegimen
>6 mos: 30 mg/kg PO x 1
Pharyngitis and Tonsillitis:
>2 years: 12 mg/kg/day PO qdx 5 days (max 500 mg/day).
Uncomplicated Chlamydial
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