3 With regard to the eye I did point out previously with regard to facial development.. oh ok.
That’s not what I want to do. Ah. That’s why. Ok, now I have my pointer.
So the eye actually begins to form completely in a lateral position. And so this is the beginning of the eye (indicated the optic vesicle, Image A)
, and over here you’re getting the
formation of the ear (indicated the Otic vesicle, Image A), which is supposed to be in a lateral position to begin with. So coming off the diencephalon, and that
’s what you’re seeing in this particular
picture, the diencephalon (Image B).
You’ll find these two structures called optic grooves.
The optic grooves enlarge and spread out and they form this structure known as an optic vesicle (Image C). The optic vesicles expand to the point that they touch the surface ectoderm. What you see in red is neural ectoderm and what you see in blue is actually the ectoderm associated with the formation of the skin. Once these two layers touch each other there
s an inductive effect that takes place. So the presence of the optic vesicle against the surface ectoderm... You have an induction where the red stimulates the blue.
And as a result you’re going to get a thickening of the surface ectoderm.
And this is the thickening (blue part of Image D). And with increased mitotic activity the thickening sort of pushes inward, and once you have a thickening of the ectoderm, we saw that happening with the formation of the nose. The nasal placode
. So we’re going to have a len
s placode and an otic placode. So this structure (indicating the lens placode of Image D) is going to invaginate inward, putting pressure on the optic vesicle. So if you compare diagram C to D, the shape of the optic vesicle
is now changing, and it’
s gone from a somewhat circular structure to something resembling a horseshoe. And this inside layer (indicating the Invaginating optic vesicle of Image D) will get pushed further inward. [Slide 3]
L17.1 EYE DEVELOPMENT DAY 22 OLDER EDITION And this is just an older version of the same picture. But I put it on because it does show
you an actual slice through, probably, a rodent head (Image D). And it’s also comparing this
picture (Image E) to the overall longitudinal view. So again we have your forebrain, your midbrain (labeled M), and your hindbrain (labeled H). And as soon as you see an opening or a hole (white arrow), you know those are the cerebral ventricles, and there are two of them. And this would be the diencephalon from which these optic grooves really originate. [Slide 4]
FIG 19.2 LENS VESICLE WEEK 6
WEEK 6.5 11
t first these pictures are a little confusing so I’m going to draw an additional picture. Let’s see how do I do this now. Not too well done but… This now shows you a C shaped
structure which in essence is this (Image B) and the optic vesicle becomes the C shaped
structure which is now referred to as an optic cup. And with this optic cup you’re going to get two layers, an inner layer and an outer layer. Here’s the inner layer and there’s the
outer layer (indicated on image C). The inner layer is much thicker and that
s what becomes the retina. The outer layer being much thinner becomes the pigmented layer of the eye. And you still have this little space between the two layers, and i
t’s known as the
intraretinal space. The lens placode which pushed inward, further develops and you get this structure known as the lens vesicle. And when you see the word vesicle there has to be some sort of space as part of the structure. A solid mass is not a vesicle. And what you have developing in this