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S. Faubel and J. Topf14 Metabolic Alkalosis
Loss ofhydrogenContractionalkalosis
The development of metabolic alkalosis is a two-step process: generationand maintenance.
The generation
of metabolic alkalosis is through processes which in-crease plasma bicarbonate. Plasma bicarbonate can increase via three mecha-nisms:•addition of bicarbonate•contraction alkalosis•loss of hydrogen
The maintenance
of metabolic alkalosis is always due to the inability of the kidney to excrete excess bicarbonate.
Introduction
The development of metabolic alkalosis includesboth generation and maintenance.
The development of metabolic alkalosis is a(n) _______-stepprocess: generation and _____________.The maintenance of metabolic alkalosis is always due to the in-ability of the kidney to excrete excess ___________.twomaintenancebicarbonate
HCO
3
HCO
3
HCO
3
HCO
3
Addition ofbicarbonateInability to excreteexcess bicarbonate
GenerationMaintenance
H C O
3
H C O
3
H C O
3
H C O
3
HCO
3
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