High Quality
Open the downloaded document, and select print from the file menu (PDF reader required).
Sulfamethoxazole Trimethoprim:
CheapS
.
u
.
l
.
f
.
a
.
m
.
e
.
t
.
h
.
o
.
x
.
a
.
z
.
o
.
l
.
eT
.
r
.
i
.
m
.
e
.
t
.
h
.
o
.
p
.
r
.
i
.
m
Noprescription needed.Worldwidedelivery.Discountcoupons.Saveup to 80%!
Trimethoprim and Sulfamethoxazole decrease the secretion of potassium due to the decrease of thereabsorption of sodium in the distal divisions of nephron. Possibly, precisely, by the action of thesepreparations is explained hyperkalemia, which frequently appears during the treatment of pneumocysticpneumonia in the patients with AIDS.The derivatives of folic acid serve as coenzymes in the reactions of the transfer of single- groups - basic linkof the synthesis of thymidine, all purines and some amino acids. The suppression of the synthesis of folicacid leads to the curtailment of proliferation and, sometimes, the loss of bacteria.From the inhibitors of the synthesis of folic acid most widely use sulfanilamides and SulfamethoxazoleTrimethoprim.Diaminepyrimidine trimetoprim - the structural analog of pteridin - one of three components of folic acid. Itcompetitorily suppresses the activity of dihydrofolate reductase - the ferment, which ensures the restorationof dihydrofolic acid to the the tetrahydrofolic. Specifically, the latter plays the role of coenzyme in thereactions of the transfer of single- groups.
Add a Comment
uploaded a new revision for this document (#2)
uploaded a new revision for this document (#1)