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Biostatistics
The null hypothesis
Null hypothesis
Types of research
Comparison
Randomised clinical trial
Randomised clinical trial - designs
Designs of a randomised clinical trial: parallel, cross-over
Cohort
Cohort studies
Progress of a cohort study
Calculation of sample size
Control group response
Type I error
Significance levels
Power
Statistical Testing Errors
Data description
Types of data
Quantitative data
Summary of measurements
Summarising data
Summarising data for the study
Measurement of location or central tendency
Mean or average
Percentile
Mode
Measure of dispersion or variability
Measure of dispersion or variability
Range or interquartile range
Measures of symmetry
Normal probability plot
Normality
Mean or median?
Generating data from sample to population
Sampling errors
Central Limit Theorem
Normal distribution
IQ Curve
Standard error SD(x)/√n
Standard error of the mean
Exercise: Calculation of SE
Comparing s and SE
Standard error of skewness
Standard error of kurtosis
Confidence limits (xx, yy)
Exercise: Calculation of CI
t distribution
Statistical tests
Tests statistics
Normal test, z test
Paired t-test
One sample t-test
Small samples, unequal SD
Comparison of several means
Analysis of variance
One-way analysis of variance
Two-way analysis of variance
Non-normal distribution
Non-parametric tests
Wilcoxon signed rank test
Wilcoxon signed (+/-) rank test
Wilcoxon rank sum test
Kruskal Wallis one way analysis of variance
Binomial distribution
The Chi-squared test for contingency tables
The Χ2 test in 2 × 2 tables
Larger tables
Goodness of fit
Paired comparison in contingency tables
Correlation and linear regression
Correlation and linear regression
Different correlations
Variance explained, r2
Regression
Linear regression
Degrees of freedom
Diagnostic tests and implications
Sensitivity
Specificity
Prediction model
Sensitivity and specificity
Predictive value of a test
Predictive value or sensitivity?
Risk and Odds and ratios
Odds
Odds ratio
Risk
Relative risk
Depends on the sample size
Confidence interval around relative risk reduction
Number to harm
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Biostatistics

# Biostatistics

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04/03/2013

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