Welcome to Scribd. Sign in or start your free trial to enjoy unlimited e-books, audiobooks & documents.Find out more
Download
Standard view
Full view
of .
Look up keyword
Like this
28Activity
0 of .
Results for:
No results containing your search query
P. 1
Absorption of Drugs

Absorption of Drugs

Ratings: (0)|Views: 1,127|Likes:
Published by alexpharm
pharmacokinetics
pharmacokinetics

More info:

Categories:Types, Research
Published by: alexpharm on Nov 05, 2009
Copyright:Attribution Non-commercial

Availability:

Read on Scribd mobile: iPhone, iPad and Android.
download as PPT, PDF, TXT or read online from Scribd
See more
See less

01/19/2014

pdf

text

original

 
 
Pharmacokinetics
Definition 
-Pharmacokinetics (in Greek:
pharmacon
meaning drug and
kinetikos
meaning putting in motion , the study of timedependency) is a branch of pharmacology dedicated to thedetermination of the fate of substances administered externallyto a living organism.
 
-Pharmacokinetics is the study and characterization of the timecourse of drugabsorption,distribution,metabolismandexcretion. This sometimes is referred to as theADMEscheme.- Pharmacokinetics also concerns the relationship of the processesto theintensityandtime courseof therapeutic andtoxicologic  effects of drugs.
 
 
Pharmacokinetics (ADME)
 
 
1.Sampling of biological speciments
--Invasive methods: Blood, spinal fluid, tissue biopsy.--Non-invasive methods: Urine, salive, feces, expired air 
Measurement of drug concentration in the blood, serum or plasma is the most directapproach to assess the pharmacokinetics of drug in body.
2.Significance of measuring plasma drug concentration
The intensity of the pharmacologic or toxic effect of a drug is oftenrelated to theconcentrationof the drug at the receptor sites.
Monitoring the concentration of drugs in the blood or plasma ascertainsthat the calculated dose actually delivers the plasma level required for therapeutic effect.
Measurement of drug concentration

Activity (28)

You've already reviewed this. Edit your review.
1 hundred reads
1 thousand reads
Jena Webb liked this
gramsharma liked this
Narendra Singh liked this
evistawin liked this
sasman liked this
Mankaran Singh liked this

You're Reading a Free Preview

Download
scribd
/*********** DO NOT ALTER ANYTHING BELOW THIS LINE ! ************/ var s_code=s.t();if(s_code)document.write(s_code)//-->